Developing Osteoporosis

The first type of medications they discussed was calcium and vitamin D supplementation. They discussed how in a few nations calcitriol and alfa calcidol have been utilized as engineered analogs of vitamin D for the treatment of osteoporosis. A meta-investigation demonstrated that vitamin D supplementation alone can't diminish break chance. In any case, the consequences of another meta-examination uncovered a break hazard diminishment at vertebral and non-vertebral locales. The useful impact of calcitriol was accounted for anticipation of bone misfortune in osteoporosis after glucocorticoid treatment or after transplantation of strong organ or undifferentiated cell. The primary unfavorable impacts of vitamin D subordinates are expanding the serum and pee level of

Osteoporosis is a disease that causes bones to become weak and fragile. While reading the controversy on page 328 in our books it was interesting to me how this disease affects people more so by their gene, sex, age, and race. What also popped out to me was how later on in life we cannot make up the calcium we failed to take in our younger years. The amount of Calcium and Vitamin D we take as children affects us all the way into our older age. Of course taking Calcium and Vitamin D at any age is better than not taking any at all, but it does not stop osteoporosis it can only slow it down.

Prior to the evolution of the newer techniques, osteoporosis was diagnosed by plain radiographs through analyzing the trabecular pattern in the upper femur and calcaneus or the cortical thinning of metacarpals and long bones (Sadat-Ali

Your calcium and vitamin D levels play a major part in preventing osteoporosis. Adults need 1000 mg of calcium every day. Women over 50 and men over 70 need to take in 1300 mg per day. Inadequate sun exposure causes a lack of vitamin D, which has a negative effect on your bones’ absorption of calcium.

Osteoporosis (OP) is a disease characterized by a low bone mass density (BMD) and a structural deterioration of bone tissue, which in most cases lead to bone fragility and increase the susceptibility to fractures (Epstein, 2006). The prevalence of OP rises with age and is more common in women than men and becomes a serious problem in postmenopausal women (Ramsubeik et al. 2013). Most cases of OP occur in postmenopausal women due to the dramatic estrogen withdrawal associated with menopause (He et al., 2010). The decrease of BMD with age is due to the increase of parathyroid hormone (PTH) secretion which results (Young et al.; 1987; Chapuy et al., 1987) from vitamin D deficiency and a low calcium adequate nutrition, especially Ca intake, plays a major role in the prevention and treatment of osteoporosis (Rizzol, 2008; Verenna, 2007) Beyond the hormonal and gene regulation, several dietary habits play a role in Ca absorption, carbohydrates, and potassium is significantly associated with fractional Ca absorption (FCA) and net Ca absorption (Ramsubeik et al. 2013).

Osteoporosis is the most frequent skeletal alteration. It is categorized as an atrophy of the bone tissue (Beskow 1997). It is a generalized, progressive diminution of bone tissue mass per unit volume, causing skeletal weakness, even though the ratio of mineral to organic elements is unchanged in the remaining morphologically normal bone. Histologically there is a reduction in cortical thickness and in the number and size of the trabeculae of cancellous bone, normal width of the osteoid seams. Bone reabsorption is increased; bone formation appears to be normal but defective (Bullock, 1984).

Calcium is also used to maintain strong bones, increase muscle movement, provide nerve impulses, keep the blood flowing (Calcium 2013) and to control the way the heart beats (Calcium 2000). Osteoporosis can happen when the body does not get enough calcium. The extreme version of this disease is called hypocalcemia which is when the body has an extremely low intake of calcium (Calcium 2015). Osteoporosis effects ¼ of the worlds population of women over 60 years old as it is the most common metabolic bone disease (Osteoporosis 2015). This disease is most commonly found in women over 40 because of the estrogen loss during menopause (Osteoporosis 2015). There is a higher chance of getting osteoporosis if a person is thin, not active, a smoker, consumes alcohol regularly or has a low calcium intake (Osteoporosis 2015). The honeycombed matrixes in bones cause them to become thinner and easier to fracture. To prevent osteoporosis a person must have good nutrition, a high intake of calcium and vitamin D and participate regularly in physical activity (Osteoporosis

Although it is clear that oestrogen deficiency significantly effects osteoporosis, it is impossible to ignore the effects of aging, poor nutrition and insufficient exercise. As we age, and bone loss begins to outweigh periosteal bone gain that is accelerated during childhood and adolescence and therefore BMD begins to decrease. Age-related bone loss is greater in women than in men. Aaron, Makins and Sagreiya state that “during the first years after the menopause, there is rapid bone loss, largely in the trabecular compartment, that leads to trabecular perforation followed by the loss of entire trabeculae” (Aaron, Makins and Sagreiya, 1987). Szule and Bouxsein also suggest that “cortical bone loss also accelerates with age and consists of cortical

Osteoporosis is a devastating bone disease in which bones become porous and brittle and are more susceptible to fractures; according to Johnell O and Kanis JA (2006), “Worldwide, osteoporosis causes more than 8.9 million fractures annually, resulting in an osteoporotic fracture every 3 seconds.” Osteoporosis is the result of several factors including diet and lifestyle choices, age, disease and medications, but the underlying cause is due to bone loss occurring faster than the body can replace it.

Osteoporosis is a condition that affects bone strength. The word osteoporosis literally means "porous bones" (Kenny). Bone is made of tough, elastic fibers and gritty, hard material minerals. It is a living tissue and contains cells that make, mold and take back up resorb bone. Initially, as a person grow, the bone tends to form faster than it is resorbed (Kenny). But, as you get older, this reverses. Around the age of 35 you will start you start to lose a certain amount of bone material overall. Your bones become less dense and less strong (Kenny). Although men can be affected by osteoporosis, older women are usually affected also. It usually hit women who has past menopause. Bone loss becomes worse in women after menopause because of the

Osteoporosis is a type of bone disease. It can be defined as the increase of bone porousness and the decrease of bone mass that can lead to fracture. It occurs as bones lose an excessive amount of their nutrient content mostly calcium. If a person having severe osteoporosis, sneeze or slight involuntary movement is enough to cause the bone to break. Common locations for osteoporosis are hip, spine, and wrist. Hip and spine fracture require hospitalization and major surgery because it can lead to other serious consequences such as permanent disability and

If viewed under a microscope the bones would look like honey combs. Bones that have Osteoporosis have lost their density or mass. They also contain abnormal tissue structure. Osteoporosis is most likely to occur in the hip, spine, or wrist; it is called a silent disease because you can’t feel the bones weakening.

The causes of osteoporosis is a lack of certain hormones, particularly estrogen in women and androgen in men. “Also inadequate intake of calcium and vitamin D, lack of weight-bearing exercise, and other age-related changes in endocrine functions (in addition to lack of estrogen)” (Driver & Stöppler). Ways to prevent osteoporosis is to “Eat a balanced diet rich in calcium and vitamin D and high in fruits and vegetables. Also, engage in weight-bearing physical exercise and adopt a healthy lifestyle with no smoking or excessive alcohol intake” (Driver & Stöppler). Also a diet rich in phosphorus and

Osteoporosis develops when there is a disparity between old bone reabsorption and new bone formation. This means that the body may be incapable of creating sufficient new bone or in some cases, there be too much reabsorption of old bone, or both. Two fundamental minerals required for formation of normal bone include phosphate and calcium. All through a person’s youth, the body utilizes these two minerals to form bones. Calcium is necessary for the apposite functioning of the brain, heart, and other organs (Carne, 2015). To ensure that these crucial organs are in good functioning capacity, the body performs calcium reabsorption, which is usually stored in the bones to ensure optimum levels of blood calcium. If calcium intake is inadequate or

Osteoporosis causes weakness of the bones and brittle in some cases stress such as turning on the bed or falling down can cause a fracture. According to mayo clinic Osteoporosis-related fractures most commonly occur in the hip, wrist or spine. Normal bones’ tissue is constantly being replaced by breaking down the old tissue bone and old bone is replaces with new bone tissue. Osteoporosis occurs when the old bone is not being replaced by new bone tissue. There are not specific races in which an individual is more prominent but men and women after menopause are more prominent to contract this disease. Aging, diet low in calcium and vitamin D, smoking, drugs and certain for example chemotherapy medication which causes bone loss, are considered to influence the risk factors in obtaining this disease.