1. (6pts) The following compound, the conjugate acid of pyridine, undergoes electrophilic aromatic substitution preferentially at the 3 position as illustrated by the synthesis of 3-nitropyridine below. NO₂ H +HNO, H₂SO4 Offer a detailed explanation (using relevant structures) for the preferential nitration at the 3 position (remember to compare to other possible products!). + H₂O
1. (6pts) The following compound, the conjugate acid of pyridine, undergoes electrophilic aromatic substitution preferentially at the 3 position as illustrated by the synthesis of 3-nitropyridine below. NO₂ H +HNO, H₂SO4 Offer a detailed explanation (using relevant structures) for the preferential nitration at the 3 position (remember to compare to other possible products!). + H₂O
Chapter22: Carbonyl Alpha-substitution Reactions
Section22.SE: Something Extra
Problem 63AP: As far back as the 16th century, South American Incas chewed the leaves of the coca bush,...
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