1. Propose a mechanism for the following transformation: R COOH (1) H₂C-O, (C₂H₂)₂NH (2) H₂O, acetate buffer R CH₂

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter22: Carbonyl Alpha-substitution Reactions
Section22.SE: Something Extra
Problem 26MP: Nonconjugated , -unsaturated ketones, such as 3-cyclohexenone, are in an acid-catalyzed equilibrium...
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1. Propose a mechanism for the following transformation:
R
COOH
(1) H₂C-O, (C₂H₂)₂NH
(2) H₂O, acetate buffer
R
CH₂
Transcribed Image Text:1. Propose a mechanism for the following transformation: R COOH (1) H₂C-O, (C₂H₂)₂NH (2) H₂O, acetate buffer R CH₂
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