11. What is the GO phase of the cell cycle? Which factors determine whether a cell enters GO? Can cells leave GO? Click on "Cell Cycle Regulators and Cancer" in the center purple circle. Read the Regulators Overview and then read through the Cancer Overview and watch the videos. 12. What are cell cycle regulators? a. Stimulatory proteins are encoded by Examples include: b. Inhibitory proteins are encoded by Examples include: 13. Cancer is the result of an improperly regulated cell cycle. Describe two reasons why cells can form tumors. 14. In some types of colon cancer, stem cells have a mutation in the APC gene. What happens if the
11. What is the GO phase of the cell cycle? Which factors determine whether a cell enters GO? Can cells leave GO? Click on "Cell Cycle Regulators and Cancer" in the center purple circle. Read the Regulators Overview and then read through the Cancer Overview and watch the videos. 12. What are cell cycle regulators? a. Stimulatory proteins are encoded by Examples include: b. Inhibitory proteins are encoded by Examples include: 13. Cancer is the result of an improperly regulated cell cycle. Describe two reasons why cells can form tumors. 14. In some types of colon cancer, stem cells have a mutation in the APC gene. What happens if the
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter28: Dna Metabolism: Replication, Recombination, And Repair
Section: Chapter Questions
Problem 19P: Figure 28.11 depicts the eukaryotic cell cycle. Many cell types “exit� the cell cycle and...
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14. In some types of colon cancer, stem cells have a mutation in the APC gene. What happens if the
APC gene is mutated?
15. Normally, proto-oncogenes stimulate the cell cycle. What are oncogenes and how do they affect
the cell cycle?
a. To cause cancer, proto-oncogenes require _________ allele(s) to be mutated and
therefore are considered ____________________. The mutation results in a __________ of
function.
16. Normally, tumor suppressor genes inhibit the cell cycle. How do mutated tumor suppressor genes
affect the cell cycle?
a. To cause cancer, tumor suppressor genes require _________ allele(s) to be mutated and
therefore are considered ____________________. The mutation results in a __________ of
function.
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