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- 1. Monoclonal antibodies. Their receipt and use in medical practice.16. A 30 year old woman with a 2-year history of systematic lupus erythematous comes to the physician for a follow-upexamination. Her condition has been well controlled for 6 months with corticosteriods. She has felt well and has not had fatigue. Menses occur at regular 28 day intervals with normal flow. Her pulse is 76/min and blood presssure is 130/80 mm Hg. Physical examination shows pale mucus membranes. Laboratory studies show Haemoglobin 10.6 g/Dl( 14 g/Dl 1 year ago) Leukocyte Count 5000/mm3 Recticulocye count 3 % Platelet count 250,000/mm3 Serum heptaglobin 30mg/Dl (N=40-200) Urine urobilinogen 3 + A peripherla blood smear shows recticulocytosis and a few spherocytes. A direct antglobulin(…III blood piasma and the chiếf antibody release during secondary responses 7. binds to the surface of mass cells and mediates an allergic response 8. predominant antibody found in mucus saliva and tears IgE IgA Match the following diseases and disorders to the correct definition. A. Allergy/Hypersensitivity B. Autoimmune Disease C. Immunodeficiency 1. AIDS & SCID 2. the immune system mounts an extraordinarily vigorous response to an otherwise harmless antigen 3. a hypersensitivity reaction 4. occurs when the production or activity of immune cells or complement is B abnormal 5. the body's own immune system produces the disorder; a breakdown of self tolerance 6. affected individuals unable to combat infections that would present no problems for normally healthy people 7. multiple sclerosis and rheumatic fever 8. a fever and contact dermatitis 9. Typical Symptoms of the acute response: tearing, runny nose, and itching skin
- 1. Serum levels of which antibody is indicative of recent infection?? which antibody isotypes remains primarily in serum? IgG, IgA, IgE, IgD, IgM2. Examples of PAMPs include. check all that apply Toll receptorsunchecked Lipopolysaccharidechecked Peptidoglycanchecked Interferonunchecked Complement91. Put the events of a type I hypersensitivity reaction in order. allergen attaches to IgE antibodies on [Choose ] mast cells [Choose ] Mast cells degranulate third first Inflammation and possibly anaphylaxis second
- 4. In teaching a patient with SLE about the disorder, the nurse knows that the pathophysiology of SLE includesA. an autoimmune T-cell reaction that results in destruction of the deep dermal skin layer.B. circulating immune complexes formed from IgG autoantibodies reacting with IgG. C. the production of a variety of autoantibodies directed against components of the cell nucleus. D. immunologic dysfunction leading to chronic inflammation in the cartilage and muscles. 5. Validating / verifying data is an activity in the assessment. What are the techniques appropriate to verify questionable information? 1. Double-check information that is inconsistent with patient cues.2. Double check that your equipment is working correctly3. Create a list of the suspected problem4. Look for factors that may alter the accuracy5. Ruling out of similar problems A. 1,2,4B. 2,3,4C. 1,2,3 D. 3,4,51. What are the functions/basic anatomy and physiology of antibodies? Please include citation (s)2. Describe briefly Rheumatoid Arthritis an autoimmune disorder according to: thanks General Characteristic/s Etiology Immunopathology/Immune manifestation Clinical Signs and Symptoms Laboratory Diagnosis Treatment