2. It is desired to examine the kinetic properties of voltage-dependent potassium channels in a ventricular cardiomyocyte. A patch - clamp experimental protocol was designed for this purpose. However, when they prepared intracellular and extracellular solutions in physiological conditions, they observed sodium, potassium and calcium currents simultaneously. In this case, they could not obtain a pure potassium channel current. b. What would you say about the voltage - and time - dependent inhibition properties of potassium channels?

2. It is desired to examine the kinetic properties of voltage-dependent potassium channels in a ventricular cardiomyocyte. A patch - clamp experimental protocol was designed for this purpose. However, when they prepared intracellular and extracellular solutions in physiological conditions, they observed sodium, potassium and calcium currents simultaneously. In this case, they could not obtain a pure potassium channel current. b. What would you say about the voltage - and time - dependent inhibition properties of potassium channels?

Biomedical Instrumentation Systems

1st Edition

ISBN:9781133478294

Author:Chatterjee

Publisher:Chatterjee

Chapter13: Artifacts And Noise In Medical Instrumentation

Section: Chapter Questions

Problem 1CS

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