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- 00 PR 3. Which of the following is characteristic of reciprocal translocation? O a. Parts of two homologous chromosomes are exchanged O b. None are characteristic of reciprocal translocation. O c. All are characteristics of reciprocal translocation O d. The carrier of a reciprocal translocation always produces offspring with normal chromosomes O e. The individual with the translocation always exhibits the abnormality. MacBook Air 888 F4 DD 00 F5 F2 F3 * 4 6. 7. D. B. NA number of genes carried on the same chromosome are tested and show the following crossover frequencies. What is their sequence in the map of the chromosome? Genes Crossover Frequencies between Them C and A 7% B and D 3% B and A 4% C and D 6% C and B 3%1. Construct a map of a chromosome containing 4 genes. Some of the distances between these genes are listed below. The distance between genes R and C is 10 units The distance between genes C and P is 13 units The distance between genes P and R is 3 units The distance between genes S and C is 18 units The distance between genes S and R is 8 units SPRC D. What two genes would likely have the most recombination events between them? S and C P and R E. What two genes would likely have the fewest recombination events between them? F. How many units are between S and P?
- An inversion heterozygote has the following inverted chromosome: Centromere ca a a A B CD JI HGF E, KL M Inverted region If a crossover occurred between genes H and I on one inverted and one normal chromosome, what would be the sequence of the dicentric chromosome before completion of metaphase I? A Cen B C D EFGHIJKL Cen M A Cen B C D JIHGFEKLM Cen JIH G F E Cen A Cen B C D JIHGFEDC B Cen A MLKEFGHIJKLM1. Which changes in chromosome structure cause a change in the total amount of genetic material, and which do not? 2. How does a chromosomal duplication occur? 3. An inversion heterozygote has the following inverted chromosome: B What would be the products if a crossover occurred between the genes F and E on the inverted chromosome and the normal chromosome? 4. An individual has the following reciprocal translocation: с D Centromere A B JI HGF ED CKLM Inverted region с D What would be the outcome of alternate segregation, adjacent -1 segregation and adjacent-2 segregation? 5. Two phenotypically unaffected parents produce two children with familial Down syndrome. Regarding chromosome 14 and 21, what are the chromosomal composition of the parents? 6. Explain how aneuploidy, deletions and duplications cause genetic imbalances. 7. Why do you think that deletions and monosomies are more detrimental than duplications and trisomies? 8. Describe some of the advantages of polyploid plants. 9.…1. In maize, the following genes are linked on chromosome 3: va - variable sterile v - virescent gl - glossy leaves Two homozygous plants were crossed and produced an all normal F1. When the F1 was test-crossed, progeny phenotypes appeared as follows: 235 virescent 7.glossy 60 wild 40 variable sterile 270 variable sterile, glossy 62 variable sterile, virescent, glossy Diagram the chromosome map for the 3 loci Example: a--1.00 cM--b--2.00 CM--c--3.00 CM Significant # of decimal places for answer: 2 Answer: 48 virescent, glossy 4 variable sterile, virescent 2. Two hypothetical autosomal human genes are 10 cM apart. These dominant alleles are completely penetrant and respectively cause crossed eyes (e+) and small thumbs (th+). A cross-eyed, small thumbed woman marries a normal man and they have 4 children. Two of the children are cross-eyed and two of the children have small thumbs. The woman is pregnant with a 5th What is the probability that this child will be cross-eyed and have small…
- A contig map for a chromosome in Drosophila is shown below. The chromosome has 10 segments, numbered 1- 10. Drosophila Chromosome 1 2 4 7 9 10 A Genomic Clones C D E If an EST hybridizes with genomic clones C, D and E, but not with the other clones, in which segment of the chromosome is the EST found? Enter a number. If a clone of gene GLO hybridizes only with genomic clones F and G, in which chromosome segment is gene GLO located? Enter a number. If a restriction fragment hybridizes with only one of the genomic clones, in which chromosome segment(s) could the fragment be found? Enter numbers for each segment ordered from smallest to largest separated by commas and no spaces. (Le. 4.8,10). A diploid strain of yeast was made by mating a haploidstrain with a genotype w−, x−, y−, and z− with a haploidstrain of opposite mating type that is wild type for thesefour genes. The diploid strain was phenotypically wildtype. Four different X-ray-induced diploid mutantswith the following phenotypes were produced fromthis diploid yeast strain. Assume a single new mutation is present in each strain.Strain 1 w− x+ y− z+Strain 2 w+ x− y− z−Strain 3 w− x+ y− z−Strain 4 w− x+ y+ z+When these mutant diploid strains of yeast go throughmeiosis, each ascus is found to contain only two viablehaploid spores.a. What kind of mutations were induced by X-rays tomake the listed diploid strains?b. Why did two spores in each ascus die?c. Are any of the genes w, x, y, or z located on thesame chromosome?d. Give the order of the genes that are found on thesame chromosome1. A mechanism for equalizing the expression of X-linked genes in males and females of a species. [ Choose ] Conjugation Reciprocal Crosses Transduction Binary Replication Haplotype Interference Transformation Gain of Function Mutation Allelic Series Blending Theory Dosage Compensation Rolling Circle Replication Pleiotropy Coefficient of Coincidence Reciprocal Cross Loss of Function Mutation Synaptonemal Complex Allelic Phase Allele Chiasma Law of Independent Assortment 2. A group of alleles of a gene that show a hierarchy of dominance relationship among them. [ Choose ] Conjugation Reciprocal Crosses Transduction Binary Replication…
- 6. A diploid strain of yeast was made by mating a haploidstrain with a genotype w−, x−, y−, and z− with a haploidstrain of opposite mating type that is wild type for thesefour genes. The diploid strain was phenotypically wildtype. Four different X-ray-induced diploid mutantswith the following phenotypes were produced fromthis diploid yeast strain. Assume a single new mutation is present in each strain.Strain 1 w− x+ y− z+Strain 2 w+ x− y− z−Strain 3 w− x+ y− z−Strain 4 w− x+ y+ z+When these mutant diploid strains of yeast go throughmeiosis, each ascus is found to contain only two viablehaploid spores.a. What kind of mutations were induced by X-rays tomake the listed diploid strains?b. Why did two spores in each ascus die?3. Six trials were run measuring recombination frequency between gene A and B. The following results were obtained Trial 1- 20% Trial 2-18% Trial 3- 22% Trail 4- 21% Trail 5-16% Trail 6-19% Calculate the Mean map distance between A and B 4. The relative location of four genes on a chromosome can be mapped from the following data on crossover frequencies Genes B and D C and A A and B C and B C and D Frequency of Crossover 5% 15% 30% 45% 50% Which of the following represents the relative positions of these four genes on the chromosome? a. ABCD b. ADCB C. CABD d. CBAD e. DBCA1. The dpy-5 gene is on Chromosome I, rol-6 on Chr II, and him-5 on Chr V. We know that the mutation for him-5 is recessive. You need to find out whether dpy-5 and rol-6 is recessive or dominant. The him-5 males carry no mutation for dpy-5 or rol-6; in other words, they have the wildtype genotype for the dpy-5 and rol-6 loci. a. In your dpy-5* him-5 cross, if dpy-5 is dominant, what do you expect to see in your F1 progeny? If dpy-5 is recessive, what do you expect? b. In your rol-6 * him-5 cross, if rol-6 is dominant, what do you expect to see in your F1 progeny? if rol-6 is recessive, what do you expect?