2. Flavopiridol was the first semi-synthetic cyclin-dependentkinase inhibitor to be tested in clinical trials. Research hasshown that co-administration of flavopiridol with drugs such asthe taxanes had synergistic cytotoxic effects against a variety oftumour cells.HOно.HOCI2.2 Name two classes of compounds that appear in the structureof flavopiridol.

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2.2 Name two classes of compounds that appear in the structure of flavopiridol.

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter21: Lipids

Section: Chapter Questions

Problem 21.78P

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2. Flavopiridol was the first semi-synthetic cyclin-dependent
kinase inhibitor to be tested in clinical trials. Research has
shown that co-administration of flavopiridol with drugs such as
the taxanes had synergistic cytotoxic effects against a variety of
tumour cells.
HO
но.
HO
CI
2.2 Name two classes of compounds that appear in the structure
of flavopiridol.

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