b. What distinct purposes do the sham-treated and untreated groups serve in thisexperiment?c. Calculate the mean and standard deviation ofdilution measurements in each group.d. We would like to test whether the meandilutions of the three groups are different.Based on your answers to parts (a) and (c),why should we be cautious about employingANOVA?e. Choose a transformation that overcomesthe main difficulty in part (d). Display yourresulting sample means and standarddeviations.f. Using the transformed data, test whetherthere is a difference among treatment groupsin the mean of dilution measurements.g. What method would we use next to helpdecide which group means differed from theothers? 24. People with an autoimmune disease like lupusproduce antibodies that react to their owntissues. Research has shown that lupus-pronestrains of mice have B cells with reduddexpression levels of the receptor gene SYRIIB,suggesting that low expression of this genemight contribute to the autoimmune reaction. Totest this, McGaha et al. (2005) experimentallyenhanced expression of the FcyRIIB gene inbone marrow taken from a lupus-prone mousestrain and transplanted it back into irradiatedmice of the same strain. Other mice of the samestrain were subjected to the same procedures butreceived bone marrow that was not enhanced forFcyRIIB expression (i.e., the sham treatment).Mice in a third group were left untreated. Auto-immune reactivity was measured six monthslater. The following is a frequency table indi-cating the highest dilution of blood serum, ina fixed series of dilutions, at which reactivitycould be detected (a high dilution reflects a highautoimmune reactivity).Dilutionmeasured100200400800TotalNumber of miceSham-Enhanced treated034209SNEOO0325Untreateda. Is this a balanced design? Explain.5524600

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Answered: 24. People with an autoimmune disease…

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

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Problem 1P

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