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- Describe several main differences in the communication methods used by the endocrine system and the nervous system.Describe one direct action of growth hormone (GH).37. An investigator is conducting a study of hormone metabolism. A compound is found that inhibits the dimerization of membrane-bound hormone receptors. Patients with which of the following conditions are most likely to benefit from this discovery? A) Acromegaly B) Cushing disease C) Graves disease D) Polycystic ovarian syndrome E) Primary hyperparathyroidism
- 76. During an in vitro experiment, it is found that glucocorticoids inhibit the growth of all neural processes, therefore controlling the morphologic characteristics of the chromaffin cells of the adrenal medulla. These modified neurons are most likely stimulated by which of the following mechanisms to release their secretory product? A) Acetylcholine release from sympathetic fibers B) Change in the rate of polymerization of metanephrine C) Decreased blood flow in cortical sinusoidal capillaries D) Downregulation of corticotropin-releasing factor E) Increased concentrations of endogenous chromogranins40. Administration of prednisone for long periods causes atrophy of which of the following endocrine structures? A) Adrenal cortex B) Adrenal medulla C) Gonads D) Parathyroid gland E) Pars intermedia of the adenohypophysisCongenital adrenal hyperplasia is a condition where individuals have a mutation in the 21 hydroxylase gene, so that the enzyme 21-hydroxylase is non functional. a)Which hormones would nit be produced in these individuals? b)What will happen to the amount of progesterone in the blood?
- 26) Which of the following hormones is categorized incorrectly? A) Testosterone-steroid B) Insulin-peptide.81. Shortly after surgical removal of the thyroid gland, a 48-year-old woman develops signs and symptoms of neuromuscular irritability, including tingling paresthesias. Gently tapping over the facial nerve in front of the ear results in reflex contraction of the facial muscles. The most likely cause of these findings is hypocalcemia due to injury to which of the following cells? A) Parathyroid oxyphil cells B) Parathyroid principal cells C) Thyroid follicular cells D) Thyroid parafollicular cells24. To be considered a target cell for a particular hormone, a cell must …. a) be experiencing a disruption in homeostasis. b) be the same cell type as the one that produced the hormone. c) be capable of producing that hormone. d) be located relatively close to the cells that produced the hormone. e) have receptors that recognize and bind to the hormone.
- 95. A 35-year-old man comes to the office because of an increase in his shoe size and enlargement of his hands. Compared with photographs obtained 10 years ago, his nose has enlarged, his lips are thickened, and he has a protruding lower jaw. Magnetization transfer imaging discloses a growth in the pituitary region suggestive of pituitary adenoma. Which of the following cells is most likely responsible for this patient's symptoms? A) Corticotroph B) Gonadotroph C) Lactotroph D) Somatotroph E) Thyrotroph13. Administration of prednisone for long periods causes atrophy of which of the following endocrine structures? A) Adrenal cortex B) Adrenal medulla C) Gonads D) Parathyroid gland OE) Pars intermedia of the adenohypophysis4. A) Define Cushing’s syndrome in terms of adrenal hormones. B) Differentiate between ACTH- and non-ACTH-dependent Cushing’s syndrome. C) Explain two reasons why a person with Cushing’s syndrome may develop Type II diabetes mellitus. D) A person with NO existing endocrine pathologies appears to be Cushingiod but actually is in an Addisonian condition. What could have happened to cause this?