3. Consider the following pedigree. Individuals with solid shapes are affected by “R disease.” 어 ㅁㅇㅇㅁㅇㅇㅁㄷ 20 a. 21 What is the inheritance pattern of R disease? How do you know? b. What are the genotypes of the numbered individuals? Remember, you need to know the inheritance pattern to answer this question.
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- . Among adults with Turner syndrome, it has beenfound that a very high proportion are genetic mosaics.These are of two types: In some individuals, themajority of cells are XO, but a minority of cellsare XX. In other Turner individuals, the majorityof cells are XO, but a minority of cells are XY.Explain how these two patterns of somatic mosaicscould arise.1. In the pedigree below, Use "A" for the allele associated with the dominant phenotype, and lowercase "a" for the allele associated with the recessive phenotype. Determine what is the most likely mode of inheritance of this disease (whether it is inherited as the result of an autosomal dominant or autosomal recessive trait). Write the most probable genotype for each individual based on the mode of inheritance you have determined. Show how all the partners are crossed and the expected offspring produced (You may use Punnett Square) 1 dró || IVII. Given the following pedigree below, use Punnett squares for each of the following possibilities: a) X- linked dominant and b) X-linked recessive in order to determine what is the mode of transmission of this trait. Disease allele = XA or Xª, depending on mode of transmission of the disease respectively. *Unaffected/No carrier-Normal Unaffected X chromosome = X I || III 1 1 2 a) X-linked recessive 9 III 6 genotype (circle one): XX * 1 2 3 11x12 4 ΧΑΧΑ 2 5 xaxa *4 6 7 8 b) X-linked dominant 11 x 12 오 XAX хах
- 12. A. B. C. A certain type of migraine headache (M) is dominant to no migraines (m). What is the genotype of a man who has migraine headaches if his father did not have them? What is the genotype of a man who has migraine headaches if his mother did not have them? If a woman without migraines marries a man who is heterozygous for migraines, what would you expect for the genotypes and phenotypes of their children? If two people who are heterozygous for migraines marry and have children, what would you expect for the genotypes and phenotypes of the children.а. What type of inheritance is shown in the pedigree? II 2 II 1 2 4 IV Identify the genotypes of the following individuals: III- 2 b. |-1 Il- 2 III-4 IV-1 + v Paragraph В I6. The pedigree below traces the inheritance of a particular disorder. Circles are females, squares are males. Shaded symbols are affected with the disorder (NOTE: "half-shaded" symbols are NOT used here, for heterozygous individuals). What is the mode of inheritance of this disorder: is it dominant or recessive? Autosomal or X-linked? What is the genotype of the three numbered individuals? 1 2. 3.
- 8. This family pedigree follows a family afflicted by a trait determined by the R gene IdA 2 9 10 11 12 13 14 15 16 17 18 19 e. What is the genotype of individual 1: f. What is the genotype of individual 6: g. What is the genotype of individual 2: h. What is the genotype of individual 13: i. Is this trait autosomal dominant, recessive, or X-linked recessive? Why? |IX. The blood of several members of a particular family was determined, and the results are tabulated below. Individual Blood Type Genotype Father Mother B Child 1 AB Child 2 B. Child 3 Grandfather (mother's side) Grandmother (father's side) AB Assuming that no adultery or adoption took place for all generations, answer the following questions: a. Give the most probable genotype for each individual. Supply your answers on the table above. b. What is/are the most probable genotype(s) for the grandmother on the mother's side? c. If the father and the mother decide to have two more children, what is the probability that the first would be female type A and the second male type AB?6. Identify the mode of inheritance for the following pedigree. Provide the genotypes of indicated individuals. ? Genotypes: Il-1 IV-1 V-6 Il-2 IV-2 V-12 Il-3 IV-3 V- 14 III-1 IV-4 V-16 III-13 V- 1 V-19
- Name: 2. Some ladybugs have 10 black spots on their shells and some have 4. When true breeding 10 spot individuals are crossed with true breeding 4 spot individuals, the offspring have 7 spots. a. Propose two distinct explanations for this finding. Explain the nature of spot inheritance in each case. D. rew bacteria erred them figure above would of14N7 then ely 2 moldon omrod abitqaq ratlsmmem sge of delw toiisoibom s s neu not oomod aid to soubnup ogusl onomod odi to slevel ismon oouborg o o consu ud od souboini bluow uoy dairlw yd za00oq sdi mialex b. Propose an experiment that would distinguish between these possibilities. sor proieins5.) A man and a woman living in a tropical area where malaria is prevalent and health care is not accessible have seven children during their lifetime. The genotypes of their children are: ss, Ss, SS, ss, Ss, Ss, and SS. What must the genotypes of both parents be? Your answer should include a Punnett square to illustrate your work, and list all the genotypes and phenotypes.11. Below is a pedigree chart of an autosomal recessive disorder. Answer the following questions using the correct genetic terminology (do not just write letters like “Ee”). A. What is the genotype of individual 1 in generation II? B: What is the genotype of individual 2 in generation I?C: Is it true that individuals 6, 7, 8, 9, and 10 in generation III all have the same genotype? Why or why not?