3:01 docs.google.com/forms 11 The energy investment of the 1/1 first stage is doubly repaid in the second stage with a net yield of two ATP per glucose. True False Glycogen degradation produces about 10% glucose, 0 of 5 rather than glucose-6- points phosphate X Explain why (Hint: think about 0/5 the enzymes involved in the glycogenolysis) When glycogen is degraded, the primary product is glucose 1P, obtained by 9 breaking a(1 → 4) glycosidic bonds. In addition, free glucose is released from

3:01 docs.google.com/forms 11 The energy investment of the 1/1 first stage is doubly repaid in the second stage with a net yield of two ATP per glucose. True False Glycogen degradation produces about 10% glucose, 0 of 5 rather than glucose-6- points phosphate X Explain why (Hint: think about 0/5 the enzymes involved in the glycogenolysis) When glycogen is degraded, the primary product is glucose 1P, obtained by 9 breaking a(1 → 4) glycosidic bonds. In addition, free glucose is released from

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter22: Gluconeogenesis, Glycogen Metabolism, And The Pentose Phosphate Pathway

Section: Chapter Questions

Problem 2P

See similar textbooks

Similar questions

Handwritten Identify the molecule names, enzyme name, enzyme classification and change in reaction(for glycolysis pathway)
Please select appropriate word in each bracket Glycogen provides short term energy storage primarily in liver and muscle. Defects in the enzymes that are required for either glycogen synthesis or breakdown therefore affect levels of [ Select ] ["glucose", "glycogen"] in the bloodstream and the amount of glycogen in the liver. This is exemplified by defects in [ Select ] ["glucose-6-phosphatase", "glycogen synthase"] , which is a deficit in breakdown and delivery, whereas mutations compromising [ Select ] ["glycogen synthase", "glycogen debranching enzyme"] result in a defect in synthesis, but defects in either enzyme produce [ Select ] ["hypoglycemia", "hypothermia"].
Glucokinase acts as a glucose sensor in hepatocytes (livercells), a- and b-cells in the pancreas, enterocytes (intestinalwall cells), and the hypothalamus (a control center in thebrain of numerous physiological processes). Explain whyglucokinase can perform this role.
, which indicates AG for each glycolytic reac- tion under intracellular conditions. Assume that glyceraldehyde-3- phosphate dehydrogenase was inhibited with iodoacetic acid. Which glycolytic intermediate would you expect to accumulate most rapidly, and why?
What is the effect of a defective a(1→ 4) phosphatase in Pompe's disease (GSD II)? O Accumulation of abnormal, unbranched glycogen, leading to heart or liver failure and short fife expectancy O Glycogen accumulation in heart, leading to heart failure, muscle weakness, short life expectancy O Absence of UDP-glucose conversion to glycogen, leading to lack of muscle glycogen, exercise intolerance Glycogen accumulation due to lack of glucose-6-phosphate conversion to glucose, leading to liver enlargement, hypoglycemia, short life expectancy O Lack of complete degradation of glycogen to glucose. leading to mild hypoglycemia, enlarged liver and muscle weakness Submit Request Answer
vat *Pyruvate carboxylase, which catalyzes conversion of pyruvate to medbo which cat oxaloacetate, is a regulatory enzyme activated by acetyl-SCOA.A ms Ido Explain why this control is advantageous to organisms. el pidotes to 316q beisbianoo olovo bios bixdio eda ei ydw ni 169qqs son esob nopyxo 16Iuselom nouods nove mellodstem Slovo od to noijose s zonado nostoals ont To 9300098 opo bias oito any contenos ain't ty dopo of basi sio S OU *While acetyl-SCOA activates pyruvate carboxylase, it inhibits pyruvate kinase. Explain how this is consistent with the idea of 9 complementary control.pе pпiwollot or to doss to slovo bios sitio :eyswdisq otlodsjem E2- noitididat xosdb99t
Compare and contrast Pyruvate Dehydrogenase with a-ketoglutarate dehydrogenaseOutline the mechanisms of both enzymes. Discuss the functions of the coenzymes. List the similarities and the differences between the 2 enzymes. Both are very large membrane bound complexes. What are the advantages of this strategy?How detailed is the enzyme structure known below(It's Pyruvate Dehydrogenase )? What insight(s) does this structural detail give you about the enzyme mechanism.
The large amount of energy used during aerobic exercise(e.g., running) requires large amounts of oxaloacetate.Explain why acetyl-CoA cannot be used to produceoxaloacetate in this circumstance. What is the sourceof oxaloacetate molecules during aerobic activity?
phosphofructokinase reaction of Fructose-2,6-bisphosphate is a regulator of both glycolysis and gluconeogenesis for the glycolysis and the fructose-1,6-bisphosphatase reaction of gluconeogenesis. In turn, the concentration of fructose-2,6-bisphosphate is regulated by many hormones, second messengers, and enzymes. Classify each condition according to its effect on glycolysis and gluconeogenesis Activates glycolysis and inhibits gluconeogenesis Activates gluconeogenesis and inhibits glycolysis Answer Bank activation of PFK-2 increased glucagon levels increased levels of cAMP increased levels of fructose-2,6-bisphosphate activation of fructose-2,6-bisphosphatase (FBPase-2)
phosphofructokinase reaction of Fructose-2,6-bisphosphate is a regulator of both glycolysis and gluconeogenesis for the glycolysis and the fructose-1,6-bisphosphatase reaction of gluconeogenesis. In turn, the concentration of fructose-2,6-bisphosphate is regulated by many hormones, second messengers, and enzymes. Classify each condition according to its effect on glycolysis and gluconeogenesis Activates glycolysis and inhibits gluconeogenesis activation of PFK-2 increased levels of cAMP Activates gluconeogenesis and inhibits glycolysis increased levels of fructose-2,6-bisphosphate activation of fructose-2,6-bisphosphatase (FBPase-2) increased glucagon levels
A sample of glycogen from a patient with liver disease is incubated with Pi, normal glycogen phosphorylase, and normal debranching enzyme. The ratio of G1P to glucose formed in the reaction mixture is 100. What is the patient’s most probable enzymatic defi ciency?
dtermoine numberof ATPS GENERATED FROM COMPLETE oxidation of fructose-6-phosphate isocitrate stearidonic acid [18 carbons triangle 6,9,12,15] indicate where everything comes from ex ATPS FROM GLYCOLYSIS , NADH FROM TCA ETC LIST ALL