4. Among the following five types of biomolecules, which is not a drug target for commercial drugs? (a) Enzymes (b) RNA (c) Carbohydrates (d) Receptors (e) DNA

Organic And Biological Chemistry
7th Edition
ISBN:9781305081079
Author:STOKER, H. Stephen (howard Stephen)
Publisher:STOKER, H. Stephen (howard Stephen)
Chapter10: Enzymes And Vitamins
Section: Chapter Questions
Problem 10.43EP
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1. Among the following five types of biomolecules, which is the least common drug target for
commercial drugs?
(a) Enzymes
(b) Receptors
(c) Carbohydrates
(d) Membrane transport proteins
(e) DNA
2. Which is a false statement regarding non-competitive enzyme inhibitor?
(a) It binds to an allosteric site of the enzyme
(b) It does not compete with the natural substrate for binding to the active site of the enzyme
(c) Its binding to the enzyme can induce a conformational change of the enzyme
(d) It can be used in combination therapies with a competitive inhibitor
(e) It usually is a mimic of the natural enzyme substrate
3. What is the purpose of structure-activity-relationship (SAR) studies?
(a) To identify the drug target
(b) To improve the pharmacokinetic properties of the drug
(c) To determine which atoms or functional groups are important to the activity of a drug
(d) To simplify the synthesis of the drug
(e) To optimise activity of the drug
4. Among the following five types of biomolecules, which is not a drug target for commercial drugs?
(a) Enzymes
(b) RNA
(c) Carbohydrates
(d) Receptors
(e) DNA
Transcribed Image Text:1. Among the following five types of biomolecules, which is the least common drug target for commercial drugs? (a) Enzymes (b) Receptors (c) Carbohydrates (d) Membrane transport proteins (e) DNA 2. Which is a false statement regarding non-competitive enzyme inhibitor? (a) It binds to an allosteric site of the enzyme (b) It does not compete with the natural substrate for binding to the active site of the enzyme (c) Its binding to the enzyme can induce a conformational change of the enzyme (d) It can be used in combination therapies with a competitive inhibitor (e) It usually is a mimic of the natural enzyme substrate 3. What is the purpose of structure-activity-relationship (SAR) studies? (a) To identify the drug target (b) To improve the pharmacokinetic properties of the drug (c) To determine which atoms or functional groups are important to the activity of a drug (d) To simplify the synthesis of the drug (e) To optimise activity of the drug 4. Among the following five types of biomolecules, which is not a drug target for commercial drugs? (a) Enzymes (b) RNA (c) Carbohydrates (d) Receptors (e) DNA
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