4. Ionization of Amino Acids. Each ionizable group of an amino acid can exist in one of two states, charged or neutral. The electric charge on the functional group is determined by the relationship between its pk, and the pH of the solution. This relationship is described by the Henderson-Hasselbalch equation. The amino acid histidine has a side chain for which the pk, is 6.0. Calculate what % of the histidine side chains will carry a positive charge at pH 5.3.

4. Ionization of Amino Acids. Each ionizable group of an amino acid can exist in one of two states, charged or neutral. The electric charge on the functional group is determined by the relationship between its pk, and the pH of the solution. This relationship is described by the Henderson-Hasselbalch equation. The amino acid histidine has a side chain for which the pk, is 6.0. Calculate what % of the histidine side chains will carry a positive charge at pH 5.3.

Fundamentals Of Analytical Chemistry

9th Edition

ISBN:9781285640686

Author:Skoog

Publisher:Skoog

Chapter21: Potentiometry

Section: Chapter Questions

Problem 21.22QAP

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