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- Can the intrinsic pathway of apoptosis be influenced or regulated by extracellular factors? DiscussCompare and contrast the intrinsic and extrinsic apoptosis pathways. Please keep brief - 3 sentences/dot points each.. Please explain the role of Ubiquitin Ligase Activity in the regulation of apoptotic cell death.
- Explain in detail (steps) how the intrinsic pathways initiates apoptosis.Describe how the Bcl2 family of protein functions to regulate apoptosis, include a specific example(s) of how it regulates?How ion channels will specifically target the cancer cell and not the normal cells or the cells which are in other physiological state (non cancerous) in apoptosis?