(a) Draw a reaction coordinate diagram (RCD) for the reaction R-[I]→P that is overall endergonic. (b) Label every TS, AG, and the AG for the reaction. (c) Graphically illustrate on the RCD that the structure of the products (P) closely matches the structure of the closest TS. (d) Illustrate the effect of adding a catalyst that lowers the activation energy of the first step of the reaction and label the rate- determining step (RDS) of your RCD.

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter14: Elimination
Section: Chapter Questions
Problem 20E
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(a) Draw a reaction coordinate diagram (RCD) for the reaction R→[I]→P that is overall endergonic. (b) Label every TS*, AG*, and the
AGO for the reaction. (c) Graphically illustrate on the RCD that the structure of the products (P) closely matches the structure of the closest
TS. (d) Illustrate the effect of adding a catalyst that lowers the activation energy of the first step of the reaction and label the rate-
determining step (RDS) of your RCD.
Transcribed Image Text:(a) Draw a reaction coordinate diagram (RCD) for the reaction R→[I]→P that is overall endergonic. (b) Label every TS*, AG*, and the AGO for the reaction. (c) Graphically illustrate on the RCD that the structure of the products (P) closely matches the structure of the closest TS. (d) Illustrate the effect of adding a catalyst that lowers the activation energy of the first step of the reaction and label the rate- determining step (RDS) of your RCD.
Each bold, capital Roman letter symbol represents one or more fundamental mechanistic steps or complex mechanisms (Handout 4B2).
Name the fundamental mechanistic step(s) or complex mechanism(s) illustrated in each reaction. Explain your choice in words using the
terminology we learned in lecture.
A
B
D
CH3
C
+
NEO
RNH₂
H3C
A
OH
H3CN=O
H
D
H
0:
H
B
v=N₂
OH
OH
H
CA
-8.²
H3C
+
CH3
RNH₂
OOH
OH
Transcribed Image Text:Each bold, capital Roman letter symbol represents one or more fundamental mechanistic steps or complex mechanisms (Handout 4B2). Name the fundamental mechanistic step(s) or complex mechanism(s) illustrated in each reaction. Explain your choice in words using the terminology we learned in lecture. A B D CH3 C + NEO RNH₂ H3C A OH H3CN=O H D H 0: H B v=N₂ OH OH H CA -8.² H3C + CH3 RNH₂ OOH OH
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