About 30 ATP are produced per glucose molecule oxidized. What would happen to the yield of ATP per glucose if the mitochondrial inner membrane suddenly became leakier? Why? What protein makes the inner-membrane leakier?
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About 30 ATP are produced per glucose molecule oxidized.
What would happen to the yield of ATP per glucose if the mitochondrial inner membrane suddenly became leakier?
Why?
What protein makes the inner-membrane leakier?
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- A new weight loss drug, Super Fat Melter, is introduced on the market but then quickly recalled after a few patients die. As it turns out, the pill makes the lipid bilayer of the inner mitochondrial membrane leaky to H+. What impact does this have on ATP production? Explain, with reference to the type of phosphorylation affected.During a 20-minute workout, a person burns 350 calories. What is the number of grams of glucose undergoing glycolysis in muscle cells with ample supply of oxygen? NADH in muscle cells is transported via the glycerol phosphate shuttle (which byhpasses Complexes I and II of the ETC). The human ATP synthase has 8 c subunits. Take note: Molar mass of glucose is 180 g/mol 1 calorie = 4.184 J phosphorylation potential in muscle cells is ~55 kJ/molHow many net ATPs would be produced if the following fatty acid is completely oxidized intocarbon dioxides and water? 94.5 96.5 98 98.5 108
- Complete catabolism of one glucose molecule yields 38 ATP molecules. How many moles of ATP are produced by the complete catabolism of 10 moles of glucose?1 a) What is meant by the ATP currency exchange ratio? Why does the oxidation of mitochondrial FADH2 generate one less ATP than oxidation of mitochondrial NADH? b) If 12 H+ are moved across the inner mitochondrial membrane by NADH oxidation, and each ATP synthesized requires 3 H+ to move through ATP synthase, why are only 3 ATP molecules produced by oxidation of each NADH?The rate of energy expenditure of a typical 70-kg person at rest is about 70 watts (W), like that of a light bulb. (a) Express this rate in kilojoules per second and in kilocalories per second. (b) How many electrons flow through the mitochondrial electron-transport chain per second under these conditions? (c) Estimate the corresponding rate of ATP production. (d) The total ATP content of the body is about 50 g . Estimate how often an ATP molecule turns over in a person at rest.
- In the presence of excess oxygen, a complete oxidation of seven molecules of glucose into carbon dioxide and water, by a yeast cell, would produce approximately ATP molecules via oxidative phosphorylation only. (Consider NADH = 3 ATP and FADH2 = 2 ATP)Where is ATP produced by oxidative phosphorylation? (where is it located immediately after the moment of synthesis) Group of answer choices the mitochondrial matrix the cytoplasm the intermembrane space the inner mitochondrial membrane Which of the following most readily donates electrons? (strongest reducing agent) Group of answer choices NADH NAD+ Ubiquinone lactate Protons first enter ATP synthase through which subunit? Group of answer choices β c γ aAssuming that the glycerol 3-phosphate shuttle is operative, a complete oxidation of three molecules of glucose (by a eukaryotic cell) into carbon dioxide and water would produce approximately ATP molecules via oxidative phosphorylation only. (Consider NADH = 2.5 ATP and FADH2 = 1.5 ATP)
- The fatty acid side chains of the phospholipids in the inner mitochondrial membrane exhibit a large proportion of multiple unsaturations. As a result, will the membrane be hydrophobic or hydrophilic? Also will it be more fluid or more rigid? How do these characteristics help explain the observation that the inner membrane is impermeable to ions such as Mg2+ and Cl–? Hint: what moves these ions through the membrane?There are some drugs that can inhibit the activity of ATP synthase. How does this affect the pH of the inner membrane space and the mitochondrial matrix?Which directions across the mitochondria must H+, ATP, ADP, and Pi travel during active mitochondrial ATP synthesis?