Albinism is a rare genetically inherited trait that is only expressed in the phenotype of homozygous recessive individuals (aa). The most characteristic symptom is a marked deficiency in the skin and hair pigment melanin. This condition can occur among humans as well as among other animal species. The average human frequency of albinism in North America is about 1 in 20,000. 1. Calculate the genotypic frequencies and place your answer below. Show your work. AA Aa aa 2. What is the percentage of carriers (heterozygotes) in the N.A. population? Edit View Insert Format Tools Table 12pt ✓ Paragraph | B IU A 2 V T² v

Albinism is a rare genetically inherited trait that is only expressed in the phenotype of homozygous recessive individuals (aa). The most characteristic symptom is a marked deficiency in the skin and hair pigment melanin. This condition can occur among humans as well as among other animal species. The average human frequency of albinism in North America is about 1 in 20,000. 1. Calculate the genotypic frequencies and place your answer below. Show your work. AA Aa aa 2. What is the percentage of carriers (heterozygotes) in the N.A. population? Edit View Insert Format Tools Table 12pt ✓ Paragraph | B IU A 2 V T² v

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter19: Population Genetics And Human Evolution

Section: Chapter Questions

Problem 9QP: Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic...

See similar textbooks

Similar questions

Cystic fibrosis is an autosomal recessive disease characterized by two copies of a mutated CFTR gene. If one in 100 (hypothetical scenario, not reality) people in the United States have cystic fibrosis, calculate the p and q frequency for the normal allele (p) and the mutated allele (q). Based on those calculations, what percentage of individuals would be expected to be homozygous dominant?
Cystic fibrosis is a homozygous recessive condition that affects 1 in 10,000 of the Hispanic populationin the United States. Calculate the frequency of the dominant allele, the frequency of the recessiveallele, and the percentage of heterozygous individuals (carriers) in the Hispanic population.Frequency of thedominant alleleFrequency of therecessive allele% homozygous dominant% homozygous recessive% heterozygous
A pedigree analysis was performed on the family of a man with schizophrenia. Based on the known concordance statistics, would his MZ twin be at high risk for the disease? Would the twins risk decrease if he were raised in an environment different from that of his schizophrenic brother?
Cystic fibrosis (CF) is one of the most common autosomal recessive disorders. 1 in 2,500 Caucasian newborns have CF. 12. The calculation that best represents the proportion of people who do not carry any alleles for CF in the Caucasian population is 1- 1/2500 √√17/2 1/2500 √1/2500 - 1 (1/2500)² The ability to taste the chemical phenylthiocarbamide (PTC) is controlled by the dominant allele T. Individuals who have the allele T find that PTC tastes bitter. Homozygous recessive individuals find that PTC has no taste. In a sample of 320 people, 218 could taste PTC and 102 could not taste PTC. 15. Which of the following rows provides the probable percentage of this population with each genotype indicated? Row 0 Genotype TT 23% 19% 44% 15% Genotype Tt Genotype tt 32% 32% 19% 56% 45% 49% 37% 29%
PLEASE ANSWER 4 & 5 Below in Figure 1 is a pedigree for a family afflicted by a genetic disorder. In some populations, Cystic fibrosis has an incidence of 1 in 2500 newborns. The carrier frequency calculated from this is 1/25. Analyze the pedigree below assuming the disease is similar to cystic fibrosis in incidence and carrier frequency. However this disease may not have the same type of genetic transmission as cystic fibrosis. What type of genetic transmission is most consistent with the pedigree? Label all the individuals that you can determine, with hypothesized genotypes. Label the individuals that have unknown genotypes with possible genotypes. Assuming her father is known to NOT be a carrier, calculate the probability that IV1 is a carrier for disease. Use the Χ2 test to determine whether your proposed transmission fits this data.
Identify each of the following as an example of allele, genotype, and/or phenotype frequency: A. Approximately 1 in 2500 people of Northern European descent is born with cystic fibrosis. B. The percentage of carriers of the sickle cell allele in West Africa is approximately 13%. C. The number of new mutations for achondroplasia, a genetic disorder, is approximately 5 × 10–5.
Consider the disease phenylketonuria (PKU), which is an autosomal recessive defect in the enzyme phenylalanine hydroxylase. The absence of the enzyme prevents phenylalanine from being metabolized causing unusually high levels of phenylalanine in the body leading to severe mental retardation. The selection coefficient for the recessive homozygous individuals is 0.7 and the frequency of the recessive allele in the population is 1.0 x 10-2. If PKU is maintained by mutation-selection balance what is the predicted mutation rate? The actual mutation rate is 1 X 10-4. What other mechanism might be affecting the allele frequency?
Cystic fibrosis (CF) recessive disorder in the Dutch population affects 1 in 1000 people. Calculate the heterozygote advantage for the cystic fibrosis gene (CFTR) in this population. Help: Square root of 0.001 is approximately equal to 0.03.
Orange coat color in cats is due to an X-linked allele (XO) that iscodominant with the allele for black (X+). When genotypes at the orangelocus were determined for a sample of cats in Minneapolis and St. Paul,Minnesota, the following data were obtained:XOXO females 11XOX+ females 70X+X+ females 94XOY males 36X+Y males 112Calculate the frequencies of the XO and X+ alleles for this population.
Consider the case of a hypothetical genetic disease called WhySciEleven (WSE), an inherited disease that results to the inability to complete production of an amino acid “moduleactivity” that results in brain damage if untreated. WSE is due to a recessive allele. Given one WSE occurrence per 10,000 births. 1. What is the frequency of the dominant allele? 2. What is the frequency of the recessive allele for WSE in population? 3. What is the frequency of the heterozygous people?
Using the two equations, p + q = 1 and p2 + 2pq + q2 = 1, answer the following questions. Maple Syrup Urine Disease (MSUD) is an autosomal recessive condition that causes intellectual and physical disabilities, difficulty feeding, and a sweet maple syrup odor to the urine. In Costa Rica, the incidence of MSUD is calculated as approximately 1 in 8,000 newborns. Calculate the allele frequencies for the normal and disease alleles.
Which of the following is a genotypic frequency? O aa = = 24% O A= 54% O a = 46% O Brown hair = 33%