Albumin is a liver protein that helps with circulation of hormones, vitamins, and enzymes throughout our body. Reduced albumin concentrations have been associated with severe ilness among individuals infected with COVID-19. Suppose we wanted to conduct a study to compare the mean Albumin concentration (gL) between a sample of adult patients hospitalized at MUSC for COVID-19 infection (328, s-6.0) to the mean Albumin concentration (gL) of healthy U.S. adults (p-34.1, on7.13). How many patients would we need to enroll from MUSC to conduct this study with 95% confidence, and 90% power? From: Chen T, Wu D, Chen H, et al. Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study (published comection appears in BMJ. 2020 Mar 31:368:m1295). BMJ. 2020,368.m1091. Published 2020 Mar 26. doi:10.1136bmj.m1091 O 269 O 164 292 O316

Linear Algebra: A Modern Introduction
4th Edition
ISBN:9781285463247
Author:David Poole
Publisher:David Poole
Chapter7: Distance And Approximation
Section7.3: Least Squares Approximation
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Albumin is a liver protein that helps with circulation of hormones, vitamins, and enzymes
throughout our body. Reduced albumin concentrations have been associated with
severe liness among individuals infected with COVID-19. Suppose we wanted to
conduct a study to compare the mean Albumin concentration (gL) between a sample of
adult patients hospitalized at MUSC for COVID-19 infection (g=32.8, s-6.0) to the
mean Albumin concentration (gL) of healthy U.S. adults (u-34.1, os7.13). How many
patients would we need to enroll from MUSC to conduct this study with 95% confidence,
and 90% power?
From: Chen T, Wu D, Chen H, et al. Clinical characteristics of 113 deceased patients
with coronavirus disease 2019: retrospective study (published correction appears in
BMJ. 2020 Mar 31;368.m 1295). BMJ. 2020;368:m1091. Published 2020 Mar 26.
doi:10.1136/bmj.m1091
O 269
O 164
O 292
O 316
Transcribed Image Text:Albumin is a liver protein that helps with circulation of hormones, vitamins, and enzymes throughout our body. Reduced albumin concentrations have been associated with severe liness among individuals infected with COVID-19. Suppose we wanted to conduct a study to compare the mean Albumin concentration (gL) between a sample of adult patients hospitalized at MUSC for COVID-19 infection (g=32.8, s-6.0) to the mean Albumin concentration (gL) of healthy U.S. adults (u-34.1, os7.13). How many patients would we need to enroll from MUSC to conduct this study with 95% confidence, and 90% power? From: Chen T, Wu D, Chen H, et al. Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study (published correction appears in BMJ. 2020 Mar 31;368.m 1295). BMJ. 2020;368:m1091. Published 2020 Mar 26. doi:10.1136/bmj.m1091 O 269 O 164 O 292 O 316
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