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- ed [Review Topics] [References] Write structures for the carbonyl electrophile and enolate nucleophile that react to give the aldol below. ОН O ● ● ● ● H You do not have to consider stereochemistry. Draw the enolate nucleophile in its carbanion form. Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate multiple reactants using the + sign from the drop-down menu. ***** ? Ⓡ ChemDoodle ↑Please complete the following self-Claisen and self-aldol reactions by drawing structures for the missing reactants or products as needed. Thank you!Aldol Condensation- Synthesis of Dibenzalacetone The protocol says that, after adding in all the reactants, stir for an additional 15 minutes. A student swirled for only 8 minutes and then, correctly, stopped and proceeded with isolating the product. What did the student do that gave such confidence and accuracy?
- This reaction is an example of conjugate addition of a nucleophile to an a,ẞ-unsaturated carbonyl. O CH3CH2CH2CH=CHCSCOA H₂O OH CH3CH2CH2CHCH2CSCOA Draw the two resonance structures of the enolate anion intermediate for this reaction. • Draw an R1 group in place of COA. The R group tool is located in the charges and lone pairs drop-down menu. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. • Separate resonance structures using the symbol from the drop-down menu. ->> 90-87 O + ? ChemDoodle >Hi! I am having a tough time trying to figure out the synthesis to this reaction. Can you help me?5. Predict the correct product for the following Aldol reaction and draw the detailed mechanism (using ChemDraw) to show how the product is formed during the reaction. Use curved arrows and lone pairs to show the electron movement in the mechanism. Refer to 'ChemDraw in Organic Chemistry' presentation slides on Canvas. te + NaOH I
- 3) Provide example reactions for Aldol and Claisen condensations. [self-study not grade: For each of your example reactions, use the product as a starting material for another reaction.]QUESTION 5 Which best explains why methyl grignard will not produce an alcohol when mixed with benzoic acid. 0 "OH +CH₂MgBr Methyl grignard will form a ketone when reacted with benzoic acid O Benzoic acid would prefer to react with itself in an aldol condensation. O Methyl grignard will add to the ring, not the carboxylic acid. O Methyl grignard will be protonated forming methane and benzoate which will not react,show the missing reagents and intermediates in the reaction sequence below