An ecologist has been following three single gene traits in laboratory breeding experiments of frogs. Texture and Color of the skin and the extent of webbing between the digits. The dominant traits in each case are Warts (vs smooth), Red (vs green) and Webbed (no-webbing). Wild type frogs have smooth, green skin with webbed feet. We want to breed a frog that has all three mutant phenotypes. Cross 1 – We made a dihybrid frog by crossing an inbred color mutant with an inbred texture mutant. Cross 2 - We crossed this dihybrid with an inbred non-webbed mutant. Part A: What is the phenotype and genotype of the dihybrid she made in cross 1, consider all three loci. For the genotype, use genetic nomenclature that is consistent with dominance and the mutant phenotype. Part B: What is the probability she will create a trihybrid from cross 2. Show your work flow.  Part C: What fraction of progeny will be the desired triple mutant from cross 2. Show your work flow, but only put your answer in the text box.

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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An ecologist has been following three single gene traits in laboratory breeding experiments of frogs. Texture and Color of the skin and the extent of webbing between the digits. The dominant traits in each case are Warts (vs smooth), Red (vs green) and Webbed (no-webbing). Wild type frogs have smooth, green skin with webbed feet.

We want to breed a frog that has all three mutant phenotypes.

Cross 1 – We made a dihybrid frog by crossing an inbred color mutant with an inbred texture mutant.

Cross 2 - We crossed this dihybrid with an inbred non-webbed mutant.

Part A: What is the phenotype and genotype of the dihybrid she made in cross 1, consider all three loci. For the genotype, use genetic nomenclature that is consistent with dominance and the mutant phenotype.

Part B: What is the probability she will create a trihybrid from cross 2. Show your work flow. 

Part C: What fraction of progeny will be the desired triple mutant from cross 2. Show your work flow, but only put your answer in the text box.

Part D: How can we maximize the chance of getting a triple mutant? You may cross any two sibling frogs that result from cross 2. What is the highest possible frequency of getting a triple mutant from crossing two sibs. Show the genotypes you propose to cross.

Part E: What is the probability that she will see wildtype males from cross 2.

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