This is one given problem on my homework assignment for developmental biology. Thank you for the help!Describe the effects of FGF and RA on each other in limb bud development. Give a specific example of their effects on each other in this capacity. Knowing this, propose a question/hypothesis to investigate the mechanism of how a specific morphogen controls pattern if you know that the morphogen is both necessary and sufficient AND is expressed in the correct spatial/temporal frame.
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This is one given problem on my homework assignment for developmental biology. Thank you for the help!
Describe the effects of FGF and RA on each other in limb bud development. Give a specific example of their effects on each other in this capacity. Knowing this, propose a question/hypothesis to investigate the mechanism of how a specific morphogen controls pattern if you know that the morphogen is both necessary and sufficient AND is expressed in the correct spatial/temporal frame.
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- Give only typing answer with explanation and conclusion topic: molec bio - cell signaling Describe the role of notch and delta in development. What is lateral inhibition? The notch/delta signaling pathway is a good example of pathways which involve signal-induced protein cleavage. How does this process regulate notch/delta function?One of the pathways required for neural tube closure is the WNT signaling pathway. The WNT receptor WLS and WNT co-receptor TMEM132a are needed for WNT secretion and signaling. Spina bifida (caudal NTD) is seen in WLS homozygous mutant mice (wwTT) as well as in TMEM132a homozygous mutant mice (WWtt). When a male mouse heterozygous for the Wls mutation (WwTT) is mated with a female mouse heterozygous for the Tmem132a mutation (WWTt), you observe ~25% of the offspring have spina bifida. A) Of the mice pups from the above cross, what genotype do you predict corresponds to the spina bifida phenotype? B) Based on your predicted genotype, what is one possible reason that these mice have spina bifida?Can I get help on creating a concept map for the Introduction provided below? The development of a multicellular organ (such as the brain) from stem cells involves complicated processing.1,2 Proliferating stem cells undergo the fate decision process before developing into tissues or organs. This process is controlled and regulated by a signaling pathway network (called gene regulatory network).3 The network comprises pathways created by the intrinsic and extrinsic factors of the cells, which form the signal transduction to control stem cell fate. There are various signal pathways that have been discovered and studied for tissue development and patterning, including Wnt signaling,4 Notch, and receptor tyrosine kinase.5–7 It has been suggested that cross-regulatory interactions between elements of the pathways (e.g., Wnt and Notch) affect the process of cell fate assignment.8,9 Most components of Wnt signaling have multiple interactions with other signaling pathways (e.g., Hippo/YAP and…
- e.html?courseld=17594778&OpenVellum HMAC-977f3bf795c701a4bc0d750e73753852#10001 hesi book PubMed Google Scholar Citation Machine®:... S StuDocu - Free sum.... omework Activity: Figure 7.31 (1 of 2) Coccyx llium Pubis Sacrum Sacroiliac joint Hip bone (coxal bone) Pubic symphysis Ischium R 2019 Pearson Education in 5 Copyright © 2022 Pearson Education Inc. All rights reserved. | Terms of Use | Privacy Policy | Permissions | Contact Us | 6 & 7 P Pearson U 8 9 O ) 0 QL study room booking P P1) Are NGN2-induced neurons (NGN2-iNs) the same as the cells in neural organoids? If not, how are they different? 2) Forced expression of the transcription factor neurogenin 2 (NGN2) induces human neurons, but to mature into electrophysiologically active neurons the require the presence of another cell type: what is that? 3)What kind of expression of NGN2 is associated with a central nervous system (CNS)-like cell? How do you know this?I am confused about how stem cell transplants works. If you put a semi differentiated tadpole nucleus in a denucleated egg cell, it’ll develop into a fully formed tadpole, but if you put a fully differentiated tadpole nucleus, it won’t (because the genes have already been expressed in a way where the cytoplasmic determinants cannot operate to the fullest). Then how come in stem cell transplants, you use adult nucleuses that are already developed and transplant them into the denucleated egg cells?
- A web.lrnr.us/courses/6241c4b1-ef4f-41db-8549-34b0c315b9f4/assignments/da0b072b-ad10-40b1-a0cb-ecc2d2baf7f5/activities/c04d4b52-bb67- irrnr laquajajones Courses > Human AP I Laboratory > Assignments > 01 Microscope Lnr HW > Peering Into the Invisible World C) Peering Into the Invisible World FIB with muitiple drop down entries 0. My Fill in the blanks, using the choices provided, to correctly identify the contributions to the Cell Theory. G2 In the late 1600s, a Dutch tailor who crafted lenses, used his primitive microscope to view pond water, the plaque In 1665, from his own oral cavity, as well as his own sperm. He referred to all of the organisms he viewed as coined the term to describe the cork tissue he was observing through a lens. You sign 91°F P Type here to searchA web.lrnr.us/courses/6241c4b1-ef4f-41db-8549-34b0c315b9f4/assignments/da0b072b-ad10-40b1-a0cb-ecc2d2baf7f5/activities/c04d4b52-bb67- irrnr laquajajones Courses > Human AP I Laboratory > Assignments > 01 Microscope Lmr HW > Peering Into the Invisible World C9 Peering Into the Invisible World FIB with muitiple drop down entries 0. My Fill in the blanks, using the choices provided, to correctly identify the contributions to the Cell Theory. G2 In the late 1600s, a Dutch tailor who crafted lenses, used his primitive microscope to view pond water, the plaque In 1665, from his own oral cavity, as well as his own sperm. He referred to all of the organisms he viewed as coined the term to describe the cork tissue he was observing through a lens. You sign 91°F P Type here to searchhow do i expand this into 1000 words The methodology employed to identify differentially expressed genes (DEGs) in breast cancer using RNA-Seq data involves several systematic steps integrating data retrieval, analysis, normalization, DEG identification, and functional annotation. Initially, raw RNA-Seq data is retrieved from the NCBI GEO database, specifically from dataset GSE216238 (Nakshatri, 2023), which encompasses samples from both breast cancer and normal tissue. Subsequently, the raw data was imported into Excel for initial analysis, leveraging its widespread availability and user-friendly interface. Gene expression data for breast cancer analysis was obtained from the Gene Expression Omnibus (GEO) database. The GEO homepage (https://www.ncbi.nlm.nih.gov/geo/) was accessed, and the "Query & Browse" tab was selected. Advanced Search: Under "Search GEO DataSets," an advanced search was conducted (https://www.ncbi.nlm.nih.gov/gds/advanced). Keywords "breast" and "cancer" were…
- How is it possible for the GABA activated chloride channel (GABA-A receptor) to switch the direction of ion flow during development? This occurs when the KCC2 transporter becomes active and transports chloride ions out of the cell to lower the chloride concentration inside the cell from 25mM to 4mM. Explain your answer using thermodynamic principles of ion flow through ion channels (passive diffusion while the channel is open). Hint: calculate deltaG (free energy change), R=8.315 J/mol *K, T=310K, F=96,500 J/(V*mol), membrane potential (delta psi) = -60mV (negative inside), Cl- concentration outside cell: 110mMHello! Discuss the onco-suppressive function of xenophagy + ( role of adaptors, compare and contrast evidence, opinion about the way forward for the field). Thank you!Shown in this diagram, describe (and connect) 5 outcomes that could occur due to loss of FMRP function in this cell. Explain your thoughts.