Are there any diseases linked to actin filaments? Are any mutations that could halt the growth of actin filaments? I've learned about different drugs that affect filaments like Phalloidin, Cytochalasin, and Latrunculin. But other than drugs, what external environmental factors could halt the process of actin filaments from growing, and is there any diseases or illness that are associated with abnormal actin filament activity?

Are there any diseases linked to actin filaments? Are any mutations that could halt the growth of actin filaments? I've learned about different drugs that affect filaments like Phalloidin, Cytochalasin, and Latrunculin. But other than drugs, what external environmental factors could halt the process of actin filaments from growing, and is there any diseases or illness that are associated with abnormal actin filament activity?

Biology: The Unity and Diversity of Life (MindTap Course List)

14th Edition

ISBN:9781305073951

Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr

Publisher:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr

Chapter35: Structural Support And Movement

Section: Chapter Questions

Problem 14SQ

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Similar questions

Can you match the sacromere anatomy with the proper answer from the list below the table graph? Sarcomere Anatomy Description/Reaction Thin Filaments ? Thick Filaments ? A Band ? I Band ? M Line ? H Zone ? Z Disc ? A) G-Actin, F-Actin, Troponin, Tropomyosin B) Myosin C) Bisected by the M Line, this area shows only the thick filaments without any thin filamentous overlap D) The point of origin for myosin filaments found in the center of the sarcomere E) An area in the center of the sarcomere marked by the entire length of the thick filaments F) A space between sarcomeres with the z-disc in the center; this region shows Actin's anchorage points and extension without myosin overlap G) Anchoring point for the thin filaments
The ability of myosin to walk along an actin filament may be observed with the aid of an appropriately equipped microscope. Describe how such assays are typically performed. Why is ATP required in these assays? How can such assays be used to determine the direction of myosin movement or the force produced by myosin?
One of the primary characteristics of all muscle tissue is contractility, the ability to shorten (contract) and lengthen (relax). You've identified the various components of a myofibril above. Now, use the table below to indicate what occurs to each band, line, or zone when the muscle contracts vs. relaxes. What occurs to this region / structure during contraction/relaxation? Region / Structure A-Band H-Band I-Band M-Line Z-Line Zone of Overlap Sarcomere No change Shortens Lengthens Muscle Contraction Muscle Relaxation
How does ADP facilitate kinesin "walking"?
Actin filaments in microvilli require the help of myosin so that they can associate with the microvilli cellular membrane. What type of myosin is utilized for membrane association? Myosin VII Myosin II O Myosin I O Myosin VI
3) Paula is a scientist who is developing a drug called Fremtol that will be used to treat muscle spasms. This drug acts on specific skeletal muscles to (1) block the release of Ca2+ ions from the sarcoplasmic reticulum, (2) inhibit the pivoting ability of the myosin heads of the thick filaments, and (3) block the production of ATP by the mitochondria in skeletal muscles. By using this drug, contraction of certain skeletal muscle fibers is reduced, which keeps those muscles from producing spasms. In the above scenario, Fremtol’s effect of blocking muscle mitochondrial ATP production would result in the inability of the muscle to make ATP from ___________. a. creatine phosphate b. anaerobic glycolysis c. aerobic respiration d. All of the above e. None of the above
What prevents the filaments from sliding back to their original position each time a myosin cross bridge detaches from actin?
There are at least 20 different types of myosin. What properties do all types share, and what makes them different?
A typical relaxed sarcomere is about 2.3 µm in length and contracts to about 2 µm in length. Within the sarcomere, the thin filaments are about 1 um long and the thick filaments are about 1.5 um long. (a) Describe the overlap of thick and thin filaments in the relaxed and contracted sarcomere. (b) An individual "step" by a myosin head in one cycle pulls the thin filament about 15 nm. How many steps must each actin fiber make in one contraction?
A typical relaxed sarcomere is about 2.3 μm in length and contracts to about2 μm in length. Within the sarcomere, the thin filaments are about 1 μmlong and the thick filaments are about 1.5 μm long.(a) Describe the overlap of thick and thin filaments in the relaxed and contracted sarcomere.(b) An individual “step” by a myosin head in one cycle pulls the thin filamentabout 15 nm. How many steps must each actin fiber make in one contraction?
Troponin C has been mutated such that it cannot bind to calcium. Describe the effect of this mutation on sarcomere shortening in skeletal muscle. A complete answer will describe the normal function of troponin C, the normal process of sarcomere shortening, and will describe the overall effect of the mutation on sarcomere shortening based on troponin C's function and its role in the overall process of sarcomere shortening.
Which of the following proteins connects the actin filaments to the Z-band in the sarcomere? CapZ Titin Profilin Nebulin O Tropomodulin < Previous