As a scientist in Company X, please design an in vitro transcription system for RNA vaccine synthesis. Please include the components required in the system and potential condition (e.g. temperature).
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As a scientist in Company X, please design an in vitro transcription system for RNA vaccine synthesis. Please include the components required in the system and potential condition (e.g. temperature).
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- Briefly explain what type of disease COVID-19 is and how it is transmitted. Select one of the approved and recommended vaccines listed on the CDC site and explain its mechanism of action, and be sure to include: Is the vaccine an mRNA or viral vector vaccine? Explain how it works within the body. How many doses are administrated? If multiple doses (or boosters) are needed, explain the importance. What are two ingredients found in the vaccine and some of the most common side effects? How do vaccines assist our immune system against emerging diseases?(a) What is the dosage form of the two above drugs? (b) What is the administration method for the two above drugs? Molnupiravir has not been approved but has been authorized for emergency use by the FDA under an EUA to treat mild to moderate COVID-19 infection. Briefly explain this decision made by FDA based on the knowledge of clinical trials. Both drugs are not allowed to be prescribed to person under 18 years old due to insufficient clinical data. Why is it necessary to separately conduct clinical trials for a younger age group?Two of the vaccines being used to prevent SARS-CoV-2 infection (the virus causing COVID-19 disease) are made of RNA sequences derived from the viral genome, which are translated into antigenic proteins in the recipient's muscle cells. This is an example of a(n): Nucleic acid vaccine Inactivated whole-agent vaccine Attenuated whole-agent vaccine Toxoid vaccine Conjugated vaccine
- Vaccines are considered an essential public health intervention for immunization against diseases. However, the said effort is challenged by the rhetorical construction of some people who oppose it (also known as anti-vaxxers). It demonstrates a violation of basic principles of ethics, especially in facing the current COVID-19 outbreak. Discuss FIVE basic principles of ethics that the anti-vaxxers have violated. Support your arguments with proper descriptions and examples.A medical technology intern was assigned to the serology section of a clinical laboratory. His supervisor asked him to prepare a 5% red cell suspension, which will be used to run a hemagglutination inhibition assay. The intern, being aware of the importance of preparing the desired concentration of red cells recommended in the assay, considers the factors enumerated on the table below during the sample processing. If you are the intern assigned to the task, explain why these factors are vital to the procedure and determine their effect on the sensitivity of the test. Factors to Consider Importance Effect 1. Tonicity of the suspending saline solution 2. Overfilling of the tube 3. Proper washing of red cells 4. Too heavy or too diluted red cell suspensionTo understand the genes responsible for growth and infectivity in a disease-causing bacterial strain, you perform chemical mutagenesis on a culture of these bacteria. In the course of your investigation into the properties of the resulting mutants, you identify a set of mutant bacteria that is still viable but their virulence is significantly impaired. How might these mutants be useful for vaccine development?
- Identify the technology portrayed by the example. Match the number to its corresponding letter. Example Technology used 1. Production of human growth hormone using genetically modified bacteria. 2. Creation of CoVid-19 vaccines that make use of viral vectors such as AstraZaneca and Sinovac. 3. Introduction of the normal CF gene to cystic fibrosis patients using adenoviruses as vectors. 4. The first bird genome to be sequenced is that of the chicken, Gallus gallus. It was completed in February 2004. This databank has been useful in the study of human diseases transmitted from birds such as the Avian flu. 5. Starting 1998, Apligraf, an engineering artificial skin has been used to replace the traditional skin grafts. a. Xenotransplantation b. GMOs as Biofactories c. Stem cell and tissue engineering d. Gene Theraphy e. Cloning by embryo splitting or nuclear transfer f. Genome projects h. Vaccine development in a shorter time framehttps://youtu.be/w7aIxiZQ60g Multiplexing agglutination https://youtu.be/uWStmyJ5Qc0 This is the multiplexing agglutination. Lab report I don’t really know what to talk about, the data, conclusions and the purpose of this. Need help pleaseIf you wanted to make an assay detecting SARS-CoV-2 virus presence, like the assay shown in the previous question, what would be a logical combination of things to include in your list of supplies to obtain? rabbit anti-SARS-cov2 spike antibody, anti-rabbit IgG horseradish peroxidase-conjugated antibody, tetramethylbenzidine rabbit anti-SARS-cov2 spike antibody, anti-mouse horseradish peroxidase conjugated antibody, tetramethylbenzidine rabbit anti-SARS-cov2 spike antibody, anti-rabbit SARS-cov2 spike antibody, tetramethylbenzidine SARS-cov2 spike, anti-rabbit IgG horseradish peroxidase-conjugated antibody, tetramethylbenzidine rabbit anti-SARS-cov2 spike horseradish peroxidase conjugated antibody, anti-rabbit horseradish peroxidase conjugated antibody, tetramethylbenzidine
- MyCalStateLA - Home atela.instructure.com/courses/76021/quizzes/346307/take/questions/5389096 Determine which of the following choices is the best match for the questions that follow: A. Whole-organism Vaccine B. Subunit Vaccine C. Toxoid Vaccine D. Experimental Vaccine Attenuated Inactivated or Killed Diphtheria Vaccine Herpes Vaccine X Recombinant-Vector Vaccine Purified macromolecule Vaccine At 3 f5 Quiz: LECTURE FINAL EXAM - MIX + 10 H 99+ f6 - [Choose ] [Choose ] [Choose ] [Choose ] [Choose ] [Choose ] 0 f7 + W f8 ((( > > > > > fg IAA по DII f11 A Next > DDI 61°F Cloudy. 4 112 It CPharmacodynamic (PD) Response Biomarkers Instructions Group (https://www.ncbi.nlm.nih.gov/books/NBK326791/), a biomarker is used to show that a biological response has occurred in an individual who has been exposed to a medical product or an environmental agent. Match the pharmacodynamic/response biomarker on the left, with the related you can use internet search, FDA According to the FDA-NIH Biomarker Working treatment/disease on the right. Please note that and NIH websites, as well as the on-line library resources. Sweat chloride Response to warfarin treatment International Effect of enzyme replacement therapy for patients with mucopolysaccharidosis type 1 normalized ratio (INR) Response to a B-lymphocyte stimulator inhibitor in patients with systemic lupus erythematosus Viral load Urinary level of glycosaminoglycans Response to cystic fibrosis transmembrane regulator (CFTR) potentiating agents in patients with cystic fibrosis Blood pressure Response to antihyperglycemic agents or…As everyone is aware of, suspected COVID-19 patients are being diagnosed using the Nasopharyngeal Swab Test through Reverse-Transcriptase Polymerase Chain Reaction. Explain its principle; its advantages and disadvantages.