AY is a 50 year old woman who was prescribed Atorvastatin (Lipitor ®) 40 mg od last week. Today, she came in complaining of muscle pain and weakness, especially in her arms and thighs. Upon going through her medical record, you found that AY is also on diltiazem 240 mg daily and omeprazole 40 mg daily. Ser565 -OH- Sere Phe423 Val683 -NH Asp690 OH OH O. H₂N H₂N NH₂ -Arg 590 H₂N Gluss H₂N Lys735 Lys 692 b) Construct a thorough structure-activity relationship (SAR) examination of all three drugs in order to make a proper therapeutic recommendation for AY.
AY is a 50 year old woman who was prescribed Atorvastatin (Lipitor ®) 40 mg od last week. Today, she came in complaining of muscle pain and weakness, especially in her arms and thighs. Upon going through her medical record, you found that AY is also on diltiazem 240 mg daily and omeprazole 40 mg daily. Ser565 -OH- Sere Phe423 Val683 -NH Asp690 OH OH O. H₂N H₂N NH₂ -Arg 590 H₂N Gluss H₂N Lys735 Lys 692 b) Construct a thorough structure-activity relationship (SAR) examination of all three drugs in order to make a proper therapeutic recommendation for AY.
Chapter13: Dimensional Analysis/units Conversion
Section: Chapter Questions
Problem 35SST
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