Both pyridine and pyrrole are nitrogen- containing aromatic heterocyclic compounds (see below). When treated with HCI, pyridine forms a hydrochloride salt, whereas pyrrole is unreactive. Provide an explanation for this observed difference in reactivity. Pyridine (pK, 8.77) = Ĥ Pyrrole (pK, 17.8) = Select one: O A. The pyrrole nitrogen is a strongly deactivating group. B. Pyrrole has a large bond angle strain, preventing it from reacting. O C. Reaction of pyrrole with HCl forms an unstable nitrogenous anion.

Both pyridine and pyrrole are nitrogen- containing aromatic heterocyclic compounds (see below). When treated with HCI, pyridine forms a hydrochloride salt, whereas pyrrole is unreactive. Provide an explanation for this observed difference in reactivity. Pyridine (pK, 8.77) = Ĥ Pyrrole (pK, 17.8) = Select one: O A. The pyrrole nitrogen is a strongly deactivating group. B. Pyrrole has a large bond angle strain, preventing it from reacting. O C. Reaction of pyrrole with HCl forms an unstable nitrogenous anion.

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter23: Amines

Section: Chapter Questions

Problem 23.72P

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Both pyridine and pyrrole are nitrogen-containing aromatic heterocyclic compounds (see below). When treated with HCI, pyridine forms a hydrochloride salt, whereas pyrrole is unreactive. Provide an explanation for this observed difference in reactivity. Pyridine (pK8.77) Pyrrole (pK, 17.8) Select one: O A. Protonation of pyrrole destroys a stable aromatic ring, while protonation of pyridine does not disrupt its aromaticity. OB. Reaction of pyrrole with HCI forms an unstable nitrogenous anion. OC. pyrdine is planar while pyrrole is not. OD. The pyrrole nitrogen is a strongly deactivating group. OE. Pyrrole has a large bond angle strain, preventing it from reacting. OF. Pyrrole is sterically hindered; pyridine is not.
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