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Briefly discuss how we can improve pharmacodynamic properties of H1-Antihistamine drugs?
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Solved in 2 steps
- what are the pharmacodynamics factors that we can improve for the H1-Antihistamine drug development?how we can improve pharmacokinetic factors( distribution) for the development of H1-Antihistamine drugs?How we can establish or improve Structure activity relationship(SAR) for the development of H1-Antihistamine drug?
- What are the potential implications of genetic variations in drug-metabolizing enzymes on individual response and therapeutic outcomes in clinical pharmacology?what is pharmacophore? what is the importance of pharmacophore in drug discovery?How we can improve pharmacodynamic parameters for the development of H1-Antihistamine ? Discuss
- How we can improve these parameters(isomerism, isosteric replacement) for the development of H1-Antihistamine drugs?How does physicochemical properties of a drug define its biological mechanism? Please explain at your own words.What are Targeted drug delivery systems ? Please explain the ideal properties of Targeted drug delivery systems?