Citrate Synthase exists as a dimer but can catalyze the formation of only 1 citrate from Acetyl-CoA + Oxaloacetate at a time O True False
Q: 182. Pyruvate dehydrogenase is inhibited allosterically by- a) AMP c) NADH b) Pyruvate d) Insulin…
A: Pyruvate dehydrogenase is regulated by :- 1) Allosteric regulation - components of PDH complex -…
Q: Oxidative deamination is also involved in the synthesis of amino acids. O True O False
A: Oxidative deamination is a process in which α-keto acids and other oxidized products from…
Q: B-oxidation of a 15:0 fatty acid will result in the production of O 7 acetyl CoA, 7 FADH2, and 7…
A: The beta oxidiation occurs in a number of the small cycle steps. Each cycle gives 1 NADh , 1…
Q: The pyruvate dehydrogenase complex catalyzes the oxidative decarboxylation of pyruvate to form…
A: The pyruvate dehydrogenase complex is an assembly of three individual enzymes: Pyruvate…
Q: High concentration of NADPH increases the rate of the pentose phosphate pathway by stimulating…
A: The pentose phosphate pathway converts glucose into ribose sugart in cytosol, the 5 step reaction…
Q: Glucagon secretion inhibits intracellular acetyl-CoA carboxylase activity through a number of…
A: The hormone glucagon is capable of regulating the activity of acetyl-CoA carboxylase. It activates…
Q: Which of the following enzymes are part of gluconeogenesis and not part of the Embden-Meyerhof…
A: Gluconeogenesis is a metabolic pathway that occurs in the liver and kidneys, it implies the…
Q: At normal to low blood glucose concentrations (l.e., roughly 110 mg/dl or less), the enzyme that is…
A: Enzymes are the type of protein that acts as biological catalysts. It speeds the rate of reaction…
Q: During fatty acid biosynthesis, propionyl CoA is the donor of the acetyl group. O True O False
A: Fatty acid biosynthesis occurs in the cytoplasm and endoplasmic reticulum of the cell. They are…
Q: Citrate carries acetyl CoA to the cytosol which is the site of fatty acid biosynthesis. O True O…
A: Fatty acid biosynthesis is the formation of fatty acids from acetyl-CoA and NADPH through the action…
Q: After several days of starvation, the ability of the liver to metabolize acetyl-CoA via the citric…
A: During starvation, glycogen stored as a fuel is used up by the liver to supply the required amount…
Q: The acyl-CoA dehydrogenase deficiency diseases are a groupof inherited defects that impair the…
A: Enzymes are the type of protein that acts as biological catalysts. It speeds the rate of reaction…
Q: A number of genetic deficiencies in acyl CoA dehydrogenases have been described. This deficiency…
A: Medium-chain acyl-coenzyme A dehydrogenase (MCAD) is one of the enzymes involved in mitochondrial…
Q: If there is an accumulation of acetyl CoA in the liver mitochondria, acetyl CoA is converted to…
A: Acetyl-CoA is formed from the end product of glycolysis i.e. pyruvate and then participates in TCA…
Q: Among the choices, I. alpha-ketoglutarate II. Glutamine III. NADPH IV. H+ which among here is the…
A: Citric acid cycle is also called as Krebs cycle.
Q: The PDH mechanism coenzyme that plays a direct role in the generation of acetyl CoA is NADH…
A: PDH means pyruvate dehydrogenase complex. This enzyme has three subunits named pyruvate…
Q: A fatty acid (a long straight-chain carboxylic acid with an even number of carbons) is metabolized…
A: The β-oxidation pathway completes the degradation of saturated fatty acids having an even number of…
Q: Ribose-5-phosphate is produced by oxidative decarboxylation of 6-phosphogluconate catalyzed by the…
A: Above questions is from PENTOSE PHOSPHATE PATHWAY.
Q: Acetyt CoA Oxaloscetate CoA NADH Citrate NAD Isocitrate Malste Pumarate NAD NADH FADH, FAD a-…
A: TCA cycle is the tricarboxylic acid cycle which is the second step in cellular respiration that…
Q: The first step in liver's metabolism of fructose is: O a. cleavage by aldolase O b. phosphorylation…
A: Fructolysis refers to the metabolism of fructose from dietary sources. Fructose is almost…
Q: . Avidin is a protein that binds extremely tightly to biotin. Therefore, it is a potent inhibitor of…
A: The correction option among the following is lactate.
Q: p) Fluoroacetate, prepared commercially for rodent control, is also produced by a South African…
A: Cellular respiration is a catabolic pathway of the process of metabolism, where a series of chemical…
Q: Acetyl CoA is essential for the synthesis of chole Tricarboxylic acid cycle operates only under ana
A: answer: B statement 1 is true statement 2 is false
Q: a. Some of the acetyl-CoA used in the citric acid cycle is produced from pyruvate. List the…
A: Glycolysis produces Pyruvate as the end result which form Acetyl CoA which initiate the citric acid…
Q: Which of the following statements is TRUE about cholesterol biosynthesis? O NADH is needed to form…
A: Introduction: Cholesterol is a fatty substance (lipid) that is essential to a healthy life and it…
Q: When the acetyl-CoA produced during ß-oxidation in the liver exceeds the capacity of the citric acid…
A: When there is an accumulation of acetyl CoA in the cell due to excessive beta-oxidation, ketone…
Q: Glycerol generated from TG hydrolysis in adipocytes is converted by the liver into _____________,…
A: Triglycerides were a derivative of glycerol which was stored as lipid in the fatty tissue. whereas…
Q: Acetyl CoA-ACP transacylase catalyzes the committed step in fatty acid biosynthesis. O True False
A: Fatty acid biosynthesis is the formation of fatty acids from acetyl CoA and NADPH through a number…
Q: The conversion of citrate to isocitrate is catalyzed by an enzyme classified as a(n): a. Hydrolase…
A: TCA cycle also called as Krebs cycle that involves the oxidation of Acetyl CoA and is the important…
Q: Conversion of amino acid nitrogen into urea by the liver for excretion normally involves all the…
A: The end products of amino acid and nucleic acid metabolism meet the urea cycle. The urea cycle is…
Q: The synthesis of the activated form of acetate (acetyl-CoA) is carried out in an ATP-dependent…
A: Acetyl CoA is the starting substrate for the TCA cycle. As mentioned that acetyl CoA synthesis is…
Q: During fatty acid biosynthesis, NADH is used as the reducing equivalent in the process. True False
A:
Q: Pyruvate dehydrogenase catalyzes the conversion of pyruvate to acetyl CoA. In this reaction, one…
A: Pyruvate dehydrogenase Enzyme is a complex of three enzymes that are important for decarboxylation…
Q: Place the events for glycolysis in the correct order. Formation of fructose-1,6-bisphosphate A…
A: Glycolysis is a process in which one mole of glucose is break down into two moles of pyruvate. It…
Q: All the reactions involved during gluconeogenesis occur in the cytosol except the one catalyzed by…
A: Gluconeogenesis is the process of synthesis of glucose from non Carbohydrate sources like aminoacids…
Q: Which of the following is NOT a fate of pyruvate in metabolism? . Conversion to alanine as its…
A: Pyruvate is the end product of glycolysis that occurs in the cytoplasm of the cell. Pyruvate…
Q: Thiolase is homologous in structure to the condensing enzyme. On the basis of this observation,…
A: Thiolases are enzymes that are involved in the mevalonate pathway. They convert two units of…
Q: What effects do the following molecules have ongluconeogenesis?a. lactateb. ATPc. pyruvated.…
A: Glucose metabolism is one of the most important parameters in the cell in terms of energy demand for…
Q: Phosphorylases and phosphatases catalyze the same reaction, the removal of a phosphate group. O True…
A: Enzymes are proteins that bind to substrate molecules and stabilise the transition state, lowering…
Q: To begin the TCA cycle, pyruvate must be converted into acetyl-Coenzyme A (acetyl-CoA) by the enzyme…
A: The TCA cycle is at the center of cellular metabolism, playing a starring role in both the process…
Q: After a carbohydrate-rich meal is consumed and the glucoserequirements of all tissues have been met,…
A: Glycogenensis is the process of the formation of glycogen from glucose. This is the energy storage…
Q: What enzyme(s) is/are specifically required for the oxidation of a Aeven monounsaturated fatty acid?…
A: Enzymes are a class of proteins that are also known as biological catalysts or biocatalysts for…
Q: Lysine can be degraded to oxaloacetate, the latter a precursor for glucose biosynthesis. True O…
A: Amino acids are primarily required for the synthesis of muscles. Some amino acids can be synthesized…
Q: Cori cycle involves the transport of lactate from skeletal muscle to the liver for gluconeogenesis…
A: Glucose is the main source of energy in the body. Glucose obtained from carbohydrate metabolism is…
Q: If Acetyl-CoA carboxylase is used to catalyze the synthesis of malonyl-coA from acetyl-CoA and…
A: Palmitate is a saturated fatty acid made up of 16 carbons. It is synthesized from acetyl CoA by the…
Q: Oxaloacetate carries acetyl CoA to the cytosol which is the site of fatty acid biosynthesis. O True…
A: Fatty acids are long chain carboxylic acid molecules. These are synthesized from acetyl CoA in the…
Q: Malonyl CoA transacylase catalyzes the committed step in fatty acid biosynthesis. O True O False
A: ACC is the first committed step in the pathway of fatty acid synthesis.
Q: Which of these enzymes is not involved in both glycolysis and gluconeogenesis Phosphoglycerate…
A: Glycolysis is the splitting of a glucose molecule into two pyruvate molecules. The glycolysis takes…
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- A Deficiency on 3-Phosphogtycerate Dehydrogenase Can Affect Amino Acid Metabolism Although serine is a nonessential amino acid, serine deficiency syndrome has been observed in humans. One such form of the syndrome is traceable to a deficiency in 3-phosphoglycerate dehydrogenase (see Figure 25.31). Individuals with this syndrome not only arc serine-deficient but also arc impaired in their ability to synthesize another common ammo acid, as well as a class of lipids. Describe why.Radiolabeling with 14C-Glutamate Describe the labeling pattern that would result from the introduction into the TCA cycle of glutamate labeled at Cy with 14C.Glucagon secretion causes inhibition of intracellular acetyl-CoA carboxylase activity by several mechanisms. Name all you can think of.
- Fatty acids are activated for breakdown through the action of acyl-CoA synthestase. Which of the following statements regarding acyl-CoA synthetase is not true? ● It catalyzes the addition of CoA to the fatty acid One of the products of the reaction is ADP. O The free energy change for the reaction catalyzed by this reaction is close to 0 kJ/mol, but the subsequent hydrolysis of pyrophosphate drives the reaction forward. O The reaction results in the formation of a thioester bond.Thiolase is homologous in structure to the condensing enzyme. On the basis of this observation, propose a mechanism for the cleavage of 3-ketoacyl CoA by CoA.The total degradation of a fatty acid with an odd number of carbons yields acetyl-CoA and another compound, X. Show the structure of X, and describe the pathway by which it is converted into a citric acid cycle intermediate, including where any cofactors participate.
- Glucagon secretion inhibits intracellular acetyl-CoA carboxylase activity through a number of different methods. Make a list of everything that comes to mind.Arrange the steps of breakdown of oleic acid (pictured below) in the correct order. 1 2 3 4 5 activation by acyl-CoAsynthe ✓ [Choose ] one cycle ofß-oxidationbeginning at the enoyl-CoAhydratasestep three cycles ofẞ-oxidation five cycles ofß-oxidation activation by acyl-CoAsynthetase enoyl-CoAisomeraseactivity enoyl-CoAisomeraseactivity V one cycle ofß-oxidationbegini V five cycles ofß-oxidation OHBehenate (C22H44O2) can be obtained by chain elongation from palmitate. How many ATP equivalents are produced in the degradation of behenate to eleven acetyl-CoA?
- Name one reaction of glycolysis, one anaplerotic reaction, and one reaction of TCA cycle that acetyl-COA allostericqally regulates ( and declare whether it is an activator or inhibitor.)Coenzyme A (CoA-SH) plays an important role in the Pyruvate Dehydrogenase Complex reaction. Which is correct? Coenzyme A serves as an electron acceptor in this reaction. The hydrolysis of a CoA thioester has a positive AG", the hydrolysis is endergonic and unfavorable. Coenzyme A is derived from thiamine, a vitamin. Coenzyme A contains -SH group and can serve as an acyl group carrier.Explain why the carbon skeletons of ketogenic amino acids yielding acetyl-CoA only cannot be converted into glucose.