Compounds A, B, C, and D are known to be intermediates in the pathway for production of protein E. To determine where the block in protein-E production occurred in each individual, the various intermediates were given to each individual’s cell in culture. After a few weeks of growth with the intermediate, the cells were assayed for the production of protein E. The results for each individual’s cells are given in the following table. A plus sign means that the protein E was produced after the cells were given the intermediate listed at the top of the column. A minus sign means that the cells still could not produce protein E even after being exposed to the intermediate at the top of the column. a) If an individual who is homozygous for the mutation found in individual 2 and heterozygous for the mutation found in individual 4 mates with an individual who is homozygous for the mutation found in individual 4 and heterozygous for the mutation found in individual 2, what could the genotypes and phenotypes of their offspring be? b) List the intermediate (if any) that would build up in each of the possible offspring.
Nucleotides
It is an organic molecule made up of three basic components- a nitrogenous base, phosphate,and pentose sugar. The nucleotides are important for metabolic reactions andthe formation of DNA (deoxyribonucleic acid) and RNA (ribonucleic acid).
Nucleic Acids
Nucleic acids are essential biomolecules present in prokaryotic and eukaryotic cells and viruses. They carry the genetic information for the synthesis of proteins and cellular replication. The nucleic acids are of two types: deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). The structure of all proteins and ultimately every biomolecule and cellular component is a product of information encoded in the sequence of nucleic acids. Parts of a DNA molecule containing the information needed to synthesize a protein or an RNA are genes. Nucleic acids can store and transmit genetic information from one generation to the next, fundamental to any life form.
Compounds A, B, C, and D are known to be intermediates in the pathway for production of protein E. To determine where the block in protein-E production occurred in each individual, the various intermediates were given to each individual’s cell in culture. After a few weeks of growth with the intermediate, the cells were assayed for the production of protein E. The results for each individual’s cells are given in the following table. A plus sign means that the protein E was produced after the cells were given the intermediate listed at the top of the column. A minus sign means that the cells still could not produce protein E even after being exposed to the intermediate at the top of the column.
a) If an individual who is homozygous for the mutation found in individual 2 and heterozygous for the mutation found in individual 4 mates with an individual who is homozygous for the mutation found in individual 4 and heterozygous for the mutation found in individual 2, what could the genotypes and
b) List the intermediate (if any) that would build up in each of the possible offspring.
Trending now
This is a popular solution!
Step by step
Solved in 3 steps
