Consider the following "pericentric" ("around the center") inversion. In one an individual, a simplified 8-gene sequence along one chromosome is 1234 5678 while a pericentric inversion occurred on their other homologous chromosome, resulting in the sequence 1265 4378 (the dot represents the centromere). Draw these homologous chromosomes lined up (as during crossing over, in Prophase l). If a crossover event occurred between gene locus 3 and 4 (slicing between them) on the original chromosome, what would the crossover products look like? What would be the "problem" with each of the chromosomes that result?

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
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Author:Michael Cummings
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Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations
Section: Chapter Questions
Problem 3QP: A colleague e-mails you saying that she has identified an interesting chromosome variation at 21q13....
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Consider the following "pericentric" ("around the center") inversion. In one an individual, a simplified 8-gene sequence along one chromosome is 1234 5678 while a pericentric inversion occurred on their other homologous chromosome, resulting in the sequence 1265 4378 (the dot represents the centromere). Draw these homologous chromosomes lined up (as during crossing over, in Prophase l). If a crossover event occurred between gene locus 3 and 4 (slicing between them) on the original chromosome, what would the crossover products look like? What would be the "problem" with each of the chromosomes that result?
3) Consider the following "pericentric" ("around the center") inversion. In one an individual, a simplified 8-gene
sequence along one chromosome is 1234 5678 while a pericentric inversion occurred on their other homologous
chromosome, resulting in the sequence 1265 4378 (the dot represents the centromere). Draw these homologous
chromosomes lined up (as during crossing over, in Prophase I). If a crossover event occurred between gene locus 3
and 4 (slicing between them) on the original chromosome, what would the crossover products look like? What
would be the "problem" with each of the chromosomes that result?
Transcribed Image Text:3) Consider the following "pericentric" ("around the center") inversion. In one an individual, a simplified 8-gene sequence along one chromosome is 1234 5678 while a pericentric inversion occurred on their other homologous chromosome, resulting in the sequence 1265 4378 (the dot represents the centromere). Draw these homologous chromosomes lined up (as during crossing over, in Prophase I). If a crossover event occurred between gene locus 3 and 4 (slicing between them) on the original chromosome, what would the crossover products look like? What would be the "problem" with each of the chromosomes that result?
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