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Define telomere and describe the possible connections between telomerase and cell aging and between telomerase and cancer.
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- draw the structure of telomeresDefine about Chromatin Remodeling ?Of the following statements related to the function of telomeres, identify which is FALSE. a. Telomeres protect organisms from cancer by limiting the number of somatic cell divisions b. Telomeres help prevent unnecessary cell death by preventing DNA monitoring activity at the staggered ends of DNA c. Telomeres restore the length of lagging DNA strands in germ cells d. Telomeres offer some protection against the unavoidable shortening of genes
- Using the figure below identify: What is the role of histones and nucleosomes? How the process of chromatin condensation is performed? What is a function of introns and exons? What is a role of mobile DNA elements? What is a meaning of simple-sequence DNA?How might our knowledge about telomeres and telomerase be applied to anti-aging strategies? Are such strategies or therapies developed?Do mutations that cause cancer in an individual pass down to his/her offspring? What is the role of proto-oncogenes and tumor-suppressor genes in cancer formation and development? Explain the connection between telomerase activity and cancer.