Do amine hormones have intracellular or cell surface receptors? Ex: epinephrine?
Do
Introduction:
Hormone travel throughout the individua's body via the bloodstream and affects the activity of its target cell only which means, only those cells having receptors for that specific hormone. Following the binding of hormone with its specific receptor, a cascade of events gets started leading to the response from the target cell. Hormones plays significant role in regulating the physiological processes. The response of the target cell makes a contribution to difference life processes for instance, human growth, reproduction, development of tissues, sleep, fluid-electrolyte balance.
The hormones produce by the individual's body can be categorized into two types based on their chemical structure. Amino acid derivative hormones are peptides, amines and proteins. Lipid derivatives are steroids hormones.
The hormones which are the derivatives of amino acids are amine hormones. The original amino acid structure is to be modified in such a way that carboxyl group () gets removed while the amine group () is still present. The amino acids tyrosine or tryptophan are responsible for synthesizing the amine hormones. For instance, Tryptophan derived hormone is melatonin, secreted by pineal gland and is responsible for the regulation of circadian rhythm. Hormones like dopamine, epinephrine, norepinephrine and thyroid hormone (T3 & T4) are derivatives of amino acid Tyrosine. Adrenal medulla secretes two hormones namely, norepinephrine and epinephrine. They are significant for the flight or fight response, while the hypothalamus secretes the hormone dopamine. It prevents the release of some hormones of anterior pituitary.
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