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Do common fungi such as bread mold produce antimicrobial compounds?
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- Mention microbial infections and most people think of hospitals, not summer camp. But being outdoors in the sunshine and fresh air is not without risk. In June 2012, a camp counselor in Omaha, Nebraska, was diagnosed with histoplasmosis, a fungal infection with symptoms similar to pneumonia: fever, headache, and respiratory distress. Although most people suffering from histoplasmosis will recover without medical treatment, the very young, very old, and people with chronic lung conditions are at greater risk for developing severe disease, which may on rare occasions prove fatal. In areas of the eastern and central United States, where Histoplasma capsulatum is endemic, dirt contaminated with bird and bat guano often contains spores of the fungus. Disturbing such contaminated dirt is a known risk factor for developing the disease. Because the sick camp counselor was one of 32 that worked at the camp, and the camp served 797 children, the Douglas County Department of Health (DCDH) and the…Propionibacterium acnes is a normal member of the skin microbiome that benefits the body by lowering the skin's pH- an antimicrobial effect. However, P. acnes is also the leading cause of acne. Explain mechanistically how can a bacterium be normal and beneficial but also be pathogenic?Why are Bacillus infections commonly associated with exposureto soil and dust?
- Propionibacterium acnes is a normal member of the skin microbiome that benefits the body by lowering the skin's pH- an antimicrobial effect. However, P. acnes is also the leading cause of acne. Explain mechanistically how can a bacterium be part of the normal microbiome and beneficial but also be pathogenic?Why are there fewer clinically effective antifungal andantiparasitic agents than antibacterial agents?Why can Koch’s postulates not be used to identify the causes of diseases due to polymicrobial infections?
- For fungal organism to be considered a "true" or "primary" pathogen it would need to be able to: Be completely nontreatable with antimicrobial agents Cause illness Invade an grow in a healthy, non-compromised host Be a member of the Candida genusWhat causes a strain of C. diphtheriae to bepathogenic? Describe how such a strain may cause deathin an infected patient?A patient suffers from chronic lung diseases, seek for a medical help. After the doctor clinical and laboratory diagnosis, he advised his patient to visit a dentist. What do you think was the doctor diagnosis, so he gave this advice to his patient? The patient has Entamoeba histolytica The patient has Ascaris lumbricoides The patient has Trichomonas tenax The patient has Taenia saginata