rcescoNOV14F2# 3Draw a linear regulatory pathway that describes this portion of themetaphase/anaphase transition pathway. Include anaphase, APC, cohesin, securin,and separase connected with activation/inhibition arrows as appropriate.ㅁㅁ 13mitoticspindleactive APC/CS4cohesincomplex000000 F4inhibitoryprotein(securin)inactiveproteolyticenzyme(separase)ci soactiveseparase54metaphaseOF516165/20attv/wwwĮ....AF6MacBook AirUBIQUITYLATION ANDDEGRADATION OFSECURIN&7cleaved anddissociated cohesinsanaphaseLF7811F8►►►9F90FIC

The cell cycle follow sequential events that involves proper growth of the cell, DNA replication,…

Draw a linear regulatory pathway that describes this portion of the metaphase/anaphase transition pathway. Include anaphase, APC, cohesin, securin, and separase connected with activation/inhibition arrows as appropriate. cohesin complex inhibitory. protein (securin) active APC/C mitotic spindle. inactive proteolytic enzyme (separase) active separase metaphase UBIQUITYLATION AND DEGRADATION OF SECURIN cleaved and dissociated cohesins anaphase

Draw a linear regulatory pathway that describes this portion of the metaphase/anaphase transition pathway. Include anaphase, APC, cohesin, securin, and separase connected with activation/inhibition arrows as appropriate. cohesin complex inhibitory. protein (securin) active APC/C mitotic spindle. inactive proteolytic enzyme (separase) active separase metaphase UBIQUITYLATION AND DEGRADATION OF SECURIN cleaved and dissociated cohesins anaphase

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter9: Cell Communication

Section: Chapter Questions

Problem 1VCQ: Figure 9.8 HER2 is a receptor tyrosine kinase. In 30 percent of human breast cancers, HER2 is...

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Figure 9.8 HER2 is a receptor tyrosine kinase. In 30 percent of human breast cancers, HER2 is permanently activated, resulting in unregulated cell division. Lapatinib, a drug used to treat breast cancer, inhibits HER2 receptor tyrosine kinase autophosphorylation (the process by which the receptor adds phosphates onto itself), thus reducing tumor growth by 50 percent. Besides autophosphorylation, which of the following steps would be inhibited by Lapatinib? Signaling molecule binding, dimerization, and the downstream cellular response. Dimerization, and the downstream cellular response. The downstream cellular response. Phosphatase activity, dimerization, and the downsteam cellular response.
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