Draw the product of the reaction of acetyl CoA with CO2 catalyzed by acetyl CoA carboxylase in the first committed step of fatty acid synthesis. Provide the structure in the protonation state found in physiological conditions. Drawing SCOA Q acetyl-COA carboxylase biotin cofactor HCO3, ATP ADP, Pi, H*
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- The Reactions and Meehanisms of the Leloir Pathway Write the reactions that permit galactose to be utilized in glycolysis. Write a suitable mechanism, tor one of these reactions.Understanding the Mechanism of the HMC-CoA Synthase Reaction Write a suitable mechanism for the HMG-CoA synthase reaction. What is the chemistry that drives this condensation reaction?Using the ActiveModel for enoyl-CoA dehydratase, give an example of a case in which conserved residues in slightly different positions can change the catalytic rate of reaction.
- Consider the docosanoic acid, C21H43CO2H a. Label the a and B carbons b. Draw the acyl CoA derived from this fatty acid c. How many acetyl CoA molecules are formed by complete B-oxidation? d. How many cycles of B-oxidation are needed for complete oxidation? e. How many molecules of ATP are formed from the complete catabolism of this fatty acid?Consider the fatty acids: (a) Arachidic acid (C20H40O2); molar mass = 312.5 g/mol) (b) Palmitoleic acid(C16H30O2); molar mass = 256.4 g/mol). i. How many cycles of β -oxidation are needed for complete oxidation?ii. How many molecules of acetyl CoA are formed from its complete catabolism?iii. Calculate the number of molecules (moles) of ATP formed (net) by the completecatabolism of each fatty acid (show your calculation).iv. Calculate number of moles of ATP formed per gram of each fatty acid metabolized.Consider docosanoic acid C12H43CO2H a. Label the alpha and beta Carbons. Show the beta-oxidation in an EXPANDED structure. b. Draw each acyl CoA derived from this fatty acid. c. How many acetyl Co A molecules are formed by complete beta-oxidation? d. How many cycles of beta-oxidation are needed for complete oxidation? e. How many molecules of ATP are formed from the complete catabolism of this fatty acid? Show the complete computation. f. How many moles of ATP per gram of fatty acid is formed from the complete catabolism of the given fatty acid? g. What is the molar mass of the given fatty acid? Solution: Show here the complete computations, [from a to e]
- All of the following are accurate contrasts for beta oxidation vs fatty acid synthesis except which of the following statements? Group of answer choices The hydroxylacyl group differs in stereochemistry between beta oxidation and biosynthesis CoA is the acyl carrier group in beta oxidation, acyl carrier protein is the carrier in biosynthesis The carbon unit resulting from beta oxidation is acetyl-CoA, the carbon unit for biosynthesis is malonyl-CoA FAD is an electron acceptor in beta oxidation, NADP+ is the electron acceptor in biosynthesisLooking at the structure of alpha linolenic acid, how many rounds of beta oxidation will occur to fully oxidize the fatty acid into acetyl CoA molecules? Please provide explanationsDraw the steps involved in the catabolism of thymine into malonyl-CoA. Include the names and structures of all metabolites as well as the names of enzymes involved.
- In the beta oxidatiin pathway when the starting fatty acid contains n carbons what is the priduct of the enzyme acyl-CoA sythetase assume the starting saturated fatty acud contains n carbons and n is an even numberWhat is the total energetics involved in the complete beta-oxidation of one mole of 19C fatty acid including the indication of the number of cycles and the number of acetylCoA produced and also the number of ATPs used and indicate clearly these reactions which are important for the generation of ATP?If the w-carbon atom of a fatty acyl CoA molecule with a C12 chain is labeled with C14, how manyrounds of β-oxidation are required to produce a radioactively labeled acetyl CoA? one two four five How many molecules of glucose are required to provide the carbon for the synthesis of onemolecule of tripalmitoylglycerol? 4.5 8.5 10.5 12.5 Need more information