Answered: Explain the factors that reactivate the…

Explain the factors that reactivate the dormant herpes simplex virus (2 pts) How can a defect in p53 gene contribute to cancer development?

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter22: Genes And Disease: Cancer

Section: Chapter Questions

Problem 4RQ

See similar textbooks

Related questions

Q: Explain the mechanism of Warburg effect and how it benefits cancer cells?

A: Warburg effect is a characteristic behavior shown by cancer cells in which their glucose uptake is…

Q: How can the role of epigenetics in cancer be reconciled with the idea that cancer is caused by the…

A: Epigenetics is the study of various alterations in an organism occurred because of certain gene…

Q: The p53 gene was discovered in 1979, but it was not clear whether the gene functioned as an oncogene…

A: An oncogene is a type of gene that is responsible for causing the cells to divide uncontrollably and…

Q: Explain how p53 functions as a tumor suppressor gene. How can mutations in p53 lead to cancer, and…

A: Normal cell has low level of p53 protein. When DNA damage or other stress signals may trigger p53…

Q: - Fraumeni Syndrome (LFS) is a rare hereditary cancer disease due to a mutation in the TP53 gene.…

A: P53 is a transcription factor and is a tumor suppressor protein synthesized by tp53 gene. P53…

Q: A normally functioning gene that regulates the cell cycle by stopping cell division is most likely…

A: Question - A normally functioning gene that regulates the cell cycle by stopping cell division is…

Q: Explain how mutations in tumor-suppressor genes can be recessive at the level of the cell but cause…

A: A tumor suppressor gene is normally a cellular gene that regulates the cell proliferation or DNA…

Q: What significance do BRCA1 and BRCA2 have in regard to developing cancer, and what types of cancer…

A: BRCA 1 & BRCA 2 are found pair in all the organisms where one gene is obtained from each of the…

Q: why EGFR play a role in CRC and other cancer?

A: EGFR : It is epidermis growth factor receptor. CRC: Colorectal cancer. EGFR : It is one of the…

Q: Explain the Role of proto-oncogenes and tumorsuppressor genes ?

A: The inactivation of tumor suppressor genes induces cancers although the activation of the…

Q: Which of the following is NOT an example of fail-safe mechanisms that prevent the irregular cell…

A: Cancer is the uncontrolled cell division where he ell continuously divides. Cancer cells thus become…

Q: a)Proteins that stimulate/promote progression through the cell cycle are encoded by (oncogenes or…

A: Hi! Thank you for the question. As you have posted a question with multiple subparts, I will be…

Q: Which genetic cancer predisposition syndrome is caused by germ-line mutations in the p53 gene and is…

A: P53 is the tumor suppressor protein (TP53 in humans) which is also described as the guardian of the…

Q: what category of cancer-related genes is it possible to find inherited variants that are associated…

A: Answer is option 3.

Q: Explain the role of epigenetic alterations in cancer ?

A: Genes are the hereditary unit in an organism and are passed on from the parental generation to the…

Q: The TP53 gene provides instructions for making a protein called tumor protein p53. Known as the…

A: Deoxyribonucleic acid, abbreviated as DNA, is a double-helix made-up of nucleic acids. Its role in…

Q: p53 is a gene / protein often associated with cancer. Why? What does p53 do? What kind of gene is…

A: p53 is a tumor suppressor gene it is called so because its activity stops the formation of…

Q: How mutations, chromosomal changes epigenetics, and environmental agents play roles in the…

A: Cancer cells breaks the most basic rule of cell behavior by which multicellular organism are built…

Q: What protein does the P53 code for and why is it important?

A: Answer :- The TP53 quality gives guidelines to making a protein called growth protein p53 (or p53).…

Q: t is the Philadelphia chromosome? Briefly describe how it causes chronic myeloid leukemia.

A: A chromosome is a dna (deoxyribonucleic acid) molecule that contains some or all of an organism's…

Q: An individual can inherit a gene in which expression has been altered by an ________ change with no…

Q: Distinguish between proto-oncogenes and tumor-suppressor genes. To become cancer promoting, do…

A: Oncogene is a type of gene having the ability which can develop a cell to a tumor cell when…

Q: The p53 gene is a tumor-suppressor gene while Ras is a proto-oncogene. Mutation in either one can…

A: Tumor suppressor genes are the genes that are involved in various checkpoints in the cell cycle,…

Q: Explain why p53 is mutated in the vast majority of human cancers.

A: Any isoform of a protein encoded by homologous genes in multiple animals, such as TP53 and Trp53, is…

Q: Describe the underlying causes of epigenetic changes associated with cancer.

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: In 2010, the U.S. Department of Health and Human Services added alcoholic beverages to its list of…

A: Cancer refers to large number of diseases that are characterized by the development of abnormal…

Q: majority of cancers in human are due to mutations in the p53 gene, however, cancers that are caused…

A: P 53 protein is also known as the tumor suppressor protein which is a type of phosphoprotein edit…

Q: Describe the steps by which the TP53 gene responds to DNA damage and/or cellular stress to promote…

A: It codes for a protein or a functional product rRNA (ribosomal RNA) or tRNA (transfer RNA). DNA is…

Q: xplain the molecular mechanisms of cancers caused by a P53 gene mutation.

A: cancer may be a disease during which a number of the body’s cells grow uncontrollably and spread to…

Q: Classify the following genes as proto-oncogenes or tumor-suppressor genes: p53, ras, Bcl-2,…

A: Proto-oncogene is a normal gene which have many different functions in the cell, like providing…

Q: Can restoring tumor suppressor function, such as mutant p53 or pRb, be used to cure cancer? If…

A: The Cell division is the process through which one cell divides into two identical daughter cells.…

Q: Genetic instability in the form of point mutations, chromosome rearrangements, and epigenetic…

A: A mutation is a form of alteration in which a single change changes a nucleotide of nucleic acid. It…

Q: Describe and explain the epidemiological evidence supporting the view that cancer develops through a…

A: Note- as we are allowed to do only one question at a time. Kindly repost the other question…

Q: How does the normal p53 protein inhibit cancer development?

A: Tumor-suppressor genes code for proteins that repair damaged DNA (preventing a cell from turning…

Q: EXPLAIN BRIEFLY: Explain the molecular mechanisms of cancers caused by a P53 gene mutation.

A: Answers P53 also defined as tumour suppressor Gene. Hence it protect the cells from various damages…

Q: Briefly explain the role of genetic testing and the following inherited gene mutations linked to…

A: Genetic testing is a type of medical test which is performe to know the defective gene or proteins…

Q: n of tu

A: Tumour suppressor genes can be defined as the gene that is involved in the regulation and…

Q: Describe how p53 functions to arrest cells in G1 and G2 stages of the cell cycle to regulate the…

A: p53 protects mammals from neoplasia by inducing apoptosis, DNA repair and cell cycle arrest in…

Q: what are the normal funtions of the p53 gene

A: p53 gene is also called as tumour suppressor gene or Tp53 gene produces the protein called tumour…

Q: Which of the following is an enabling characteristic for cancer that can increase the likelihood of…

A: The somatic mutations in the genome of a cancer cell, irrespective of their structural nature, can…

Q: What is the role of regulatory gene mutations in cancer?

A: Regulatory genes are defined as genes which control or regulate the expression of one or multiple…

Q: . Why is chronic inflammation a risk factor for cancers? Indicate as many answers as apply. O…

A: In chronic inflammation, the process of inflammation begins even if no injury does not end. An…

Q: Please explain the relationship between proto-oncogenes and the cell cycle. Then describe three…

A: The cell cycle has several checkpoints which regulate the various stages of cell cycle. There are…

Q: Which of the following must occur for programmed cell death (apoptosis): 1. p53 must be stabilized…

A: Apoptosis is called as the programmed death of the cell which is controlled genetically. The protein…

Q: what are the rolls that the p53 gene and RAS protein take on when trying to stop a cancer cell from…

A: Given: Role of p53 and RAS protein to stop a cancer cell from replication. What happens if mutation…

Q: As the most junior member of a lab, you are tasked with generating cell lines that accumulate DNA…

A: If DNA damage occurs then the cell cycle will be arrested and the cell try to repair the damaged…

Question

Explain the factors that reactivate the dormant herpes simplex virus (2 pts)

How can a defect in p53 gene contribute to cancer development? (2 pts)

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Step 3

VIEW

Step by step

Solved in 3 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.

Similar questions

Explain Three mechanisms for viral induction of cancer.
-Describe the seven hallmarks of cancer i) List the seven hallmarks ii) Connect each hallmark to the type of change -Explain importance of p53 i) Know the function of p53 ii) Explain how loss of p53 can result in several hallmarks of cancer
how is activating invasion and metastasis necessary for cancer development and how is it a driving cancer formation. explain in 3-6 sentences.
Name the cancer causing agents.
List 3 causes of cancer:
Tissues and differentiation a)Explain what is meant by termination and differentiation ).b) Explain the difference between an oncogenic and a tumour suppressor gene and describe how they are involved in the onset of cancer
1. Describe & explain the pathophysiology of cancer based on the diagram. Reference: https://www.onlinebiologynotes.com/cancer-etiology-pathophysiology-types-diagnosis-and- treatment/ Acquired (environmental) DNA damaging agents: • chemical • radiation viruses Activation of growth- promoting oncogenes NORMAL CELL DNA Damage Failure of DNA repair Mutations in the genome of somatic cells Alteration of genes that regulate apoptosis Malignant neoplasm / Successful DNA repair CANCER Inherited mutations: • Genes affecting DNA repair • Genes affecting cell growth Expression of altered gene products and loss of regulatory gene products Inactivation of cancer suppresor genes Clonal expansion Additional mutations (progression) T Heterogeneity
how are the hallmarks resisting cell death and enabling replicative immortality essential for cancer development. explain each in 3-5 sentences.
What are cancer-specific considerations?
1)Briefly describe three chemical factors affecting cell division. 2)Briefly describe the three classifications of cancer based on origin.
How do virus infection and chemicals may cause cancer? Give examples and mechanisms.
Please discuss the difference between cancers caused by tumor viruses and cancers caused by oncogenes. Does the etiology of a cancer influence its manifestation?