Geneticists have been exploring ways to suppress the expression of the extra chromosome 21 in individuals with Down syndrome in hopes of preventing the medical problems and intellectual disability of individuals with trisomy 21. One approach involves modifying a gene that is already present in human cells and using it to suppress the expression of the extra copy of chromosome 21. What approach, do you think, are they taking, and what may be some of the challenges for using it in patients?

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
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Chapter15: Genomes And Genomics
Section: Chapter Questions
Problem 14QP
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Geneticists have been exploring ways to suppress the expression of the
extra chromosome 21 in individuals with Down syndrome in hopes of
preventing the medical problems and intellectual disability of
individuals with trisomy 21. One approach involves modifying a gene
that is already present in human cells and using it to suppress the
expression of the extra copy of chromosome 21. What approach, do
you think, are they taking, and what may be some of the challenges for
using it in patients?

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