Group 3) Replacing an A with a T in a hemoglobin gene is associated with sickle-cell anemia in humans. Normal: 5'- ATGGTGCACCTGACTCCTGAGGAGAAGTCT-3' ATGGTGCACCTGACTCCTGTGGAGAAGTCT-3' Sickle cell: 5'- (a) What is the nucleotide sequence of the normal and sickle-cell hemoglobin mRNA? (b) What is the amino acid sequence in this part of the polypeptide chain, and what is the amino acid replacement that results in sickle-cell hemoglobin? (c) Why might this amino acid substitution make a difference in protein structure?

Group 3) Replacing an A with a T in a hemoglobin gene is associated with sickle-cell anemia in humans. Normal: 5'- ATGGTGCACCTGACTCCTGAGGAGAAGTCT-3' ATGGTGCACCTGACTCCTGTGGAGAAGTCT-3' Sickle cell: 5'- (a) What is the nucleotide sequence of the normal and sickle-cell hemoglobin mRNA? (b) What is the amino acid sequence in this part of the polypeptide chain, and what is the amino acid replacement that results in sickle-cell hemoglobin? (c) Why might this amino acid substitution make a difference in protein structure?

Name: Give typed full explanation Group 3) Replacing an A with a T in a hemo
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Description: Give typed full explanation Group 3) Replacing an A with a T in a hemoglobin geneassociated with sickle-cell anemia in humans.Normal:5'-ATGGTGCACCTGACTCCTGAGGAGAAGTCT-3'ATGGTGCACCTGACTCCTGTGGAGAAGTCT-3'Sickle cell:5'-(a) What is the nucleotide sequen

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter16: Human Genetics And The Human Genome

Section: Chapter Questions

Problem 6TYU

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