HDL-R: HDLS carry cholesterol to the liver for elimination. Liver cells respond to estrogen to express a protein receptor for HDLS coded by the HDL-R gene (HDL-R gene contains an estrogen response element.) PFK: codes for an enzyme called phosphofructokinase that is used in the first steps of breaking down glucose for energy in all cells. (Gene has no estrogen response element.) CD3: codes for a cell surface protein produced by immune B cells (Gene has no estrogen response element) If estrogen circulates and reaches all cells in the body, how is the HDL receptor protein produced in liver but not in immune cells? O Immune cells are not exposed to high enough levels estrogen to stimulate transcription ofHDL-R into mRNA. O Immune cells have inactivated the estrogen response element in order to prevent expression of this genes that they don't need. O The HDL-R gene in immune cells lacks an estrogen response element in the upstream DNA.

HDL-R: HDLS carry cholesterol to the liver for elimination. Liver cells respond to estrogen to express a protein receptor for HDLS coded by the HDL-R gene (HDL-R gene contains an estrogen response element.) PFK: codes for an enzyme called phosphofructokinase that is used in the first steps of breaking down glucose for energy in all cells. (Gene has no estrogen response element.) CD3: codes for a cell surface protein produced by immune B cells (Gene has no estrogen response element) If estrogen circulates and reaches all cells in the body, how is the HDL receptor protein produced in liver but not in immune cells? O Immune cells are not exposed to high enough levels estrogen to stimulate transcription ofHDL-R into mRNA. O Immune cells have inactivated the estrogen response element in order to prevent expression of this genes that they don't need. O The HDL-R gene in immune cells lacks an estrogen response element in the upstream DNA.

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter4: Principles Of Neural And Hormonal Communication

Section: Chapter Questions

Problem 18RE

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HDL-R: HDLS carry cholesterol to the liver for elimination. Liver cells respond to estrogen to express a protein receptor for HDLS coded by the HDL-R gene (HDL-R gene contains an estrogen response element.) PFK: codes for an enzyme called phosphofructokinase that is used in the first steps of breaking down glucose for energy in all cells. (Gene has no estrogen response element.) CD3: codes for a cell surface protein produced by immune B cells (Gene has no estrogen response element) Which of the following describes differences in the HDL-R gene in liver & immune cells? O The immune cell has permanently altered the HDL-R gene so that it can no longer be transcribed. O The immune cell has removed the estrogen response element from the HDL-R gene so that it cannot be transcribed. No difference O Only the liver cell retains the HDL-R gene, the immune cell has lost it.
HDL-R: HDLs carry cholesterol to the liver for elimination. Liver cells respond to estrogen to express a protein receptor for HDLs coded by the HDL-R gene (HDL-R gene contains an estrogen response element.) PFK: codes for an enzyme called phosphofructokinase that is used in the first steps of breaking down glucose for energy in all cells. (Gene has no estrogen response element.) CD3: codes for a cell surface protein produced by immune B cells (Gene has no estrogen response element)mRNA transcripts can be collected from cells, made to glow with a fluorescent dye, and added to a microarray chip containing spots with DNA sequences from each of these genes. (In the depiction of the microarrays below ○ indicates no binding of the mRNA, and ● indicates binding.)Which of the gene expression patterns would you expect to see if you used mRNA from immune B cells to add to the microarray?
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