hen an action potential arrives at the nerve terminal of a neuromuscular junction, which of the following statements best describes the events that occur?
hen an action potential arrives at the nerve terminal of a neuromuscular junction, which of the following statements best describes the events that occur?
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Depolarisation of the nerve terminal causes the release of ACh which activates nicotinic receptors on the skeletal muscle membrane to cause Ca2+ entry and muscle contraction. |
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Depolarisation of the nerve terminal opens voltage-gated Ca2+ channels, Ca2+ entry brings vesicles containing ACh to the membrane which form fusion pores causing the release of ACh which activates voltage-gated Na+ channels at the end-plate. |
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Depolarisation of the nerve terminal opens voltage-gated Ca2+ channels, Ca2+ entry brings vesicles containing ACh to the membrane which form fusion pores causing the release of ACh which binds to muscarinic receptors at the end plate. |
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Depolarisation of the nerve terminal opens voltage-gated Ca2+ channels, Ca2+ entry brings vesicles containing ACh to the membrane which form fusion pores causing the release of ACh which binds to ligand gated cation channels at the end-plate. |
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