In the absence of the drug, Xor's blood pressure would drop as low as 70 mmHg. As the blood pressure falls to 70 mm Hg, how much drug should we administer to restore the blood pressure to 105 mmH? To answer this question, assume the following conditions: 1. the drug directly affects the rate of blood flow from the heart (L/min), 2. the drug has no effect at dosages below 41 g and has a linear effect on the rate of blood flow at dosages above 41 g. The slope of this linear effect is 2.91 (L/min) / g of drug, and 3. the drug must increase the rate of blood flow enough to increase the blood pressure from 70 mm Hg to 105 mmHg, and 4. the slope of the linear relationship between the rate of blood flow from the heart and the blood pressure in megaraffes is 0.225 mmHg/(L/min). Our goal is to determine the dosage of the drug needed to increase the blood pressure by 35 mmHg. We'll work backwards from this goal to determine the correct dose.
In the absence of the drug, Xor's blood pressure would drop as low as 70 mmHg. As the blood pressure falls to 70 mm Hg, how much drug should we administer to restore the blood pressure to 105 mmH? To answer this question, assume the following conditions: 1. the drug directly affects the rate of blood flow from the heart (L/min), 2. the drug has no effect at dosages below 41 g and has a linear effect on the rate of blood flow at dosages above 41 g. The slope of this linear effect is 2.91 (L/min) / g of drug, and 3. the drug must increase the rate of blood flow enough to increase the blood pressure from 70 mm Hg to 105 mmHg, and 4. the slope of the linear relationship between the rate of blood flow from the heart and the blood pressure in megaraffes is 0.225 mmHg/(L/min). Our goal is to determine the dosage of the drug needed to increase the blood pressure by 35 mmHg. We'll work backwards from this goal to determine the correct dose.
Biomedical Instrumentation Systems
1st Edition
ISBN:9781133478294
Author:Chatterjee
Publisher:Chatterjee
Chapter9: Instrumentation In Blood Circulation
Section: Chapter Questions
Problem 4P
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