magine that you created a cell that over-expresses a truncated version of its extrinsic pathway initiator caspase. This protein contains the caspase's DED, but mone of the caspase's protease domains. This truncated version is present as an extra copy in addition to the WT copy. In 1-2 sentences, explain what the outcome would be on extrinsic apoptosis (i.e. would it be a positive/negative regulator/have no effect) and why.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Imagine that you created a cell that over-expresses a truncated version of its
extrinsic pathway initiator caspase. This protein contains the caspase's DED, but
none of the caspase's protease domains. This truncated version is present as an extra
copy in addition to the WT copy.
In 1-2 sentences, explain what the outcome would be on extrinsic apoptosis (i.e.
would it be a positive/negative regulator/have no effect) and why.
Transcribed Image Text:Imagine that you created a cell that over-expresses a truncated version of its extrinsic pathway initiator caspase. This protein contains the caspase's DED, but none of the caspase's protease domains. This truncated version is present as an extra copy in addition to the WT copy. In 1-2 sentences, explain what the outcome would be on extrinsic apoptosis (i.e. would it be a positive/negative regulator/have no effect) and why.
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