Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter50: Reproduction
Section: Chapter Questions
Problem 15TYU: Test Your Understanding 15 SCIENCE, TECHNOLOGY, AND SOCIETY Why do you think that a variety of...
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Question
1. Predict the fertilization problems if the Ca+2 wave gets blocked?
2. One of the goals of modern-day pharmacology is to develop a male contraceptive.
Go through the steps of fertilization and determine what steps do you think it might be possible to block
pharmacologically in order to produce such a contraceptive for males?
Expert Solution
Step 1
- The process of fertilization involves a sperm fusing with an ovum. The sperm plasma then fuses with the egg's plasma membrane.
- The result of this union, leads to the production of a zygote cell or fertilized egg, initiating prenatal development.
use of calcium in fertilization and in early development
- which an activating substance enters the egg from the sperm on sperm-egg fusion, activating the egg by stimulating phospholipase C activation through a src family kinase pathway and in mammals by the diffusion of a sperm-specific phospholipase C from sperm to egg on sperm-egg fusion.
- The fertilization calcium wave is then set into the context of cell cycle control and the mechanism of repetitive calcium spiking in mammalian eggs is investigated.
- calcium signals control cell division in early embryos and that calcium signals are essential at all three stages of cell division in early embryos.
- phosphoinositide signaling pathways control the resumption of meiosis during oocyte maturation is considered
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