MRI and PET scans have shown that patients at early stages of Alzheimer’s disease have medial temporal lobe atrophy and decreased neural activity in the parietal lobe and frontal lobe. Identify the symptoms of early onset Alzheimer’s disease that can result from these affected areas of the brain listed below. • Medial temporal lobe • Parietal lobe • Frontal lobe
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- Histological and brain imaging methods can be used to detect or confirm Alzheimer’s disease. Select ALL that apply: Functional MRI imaging of neuronal activity during episodic memory tasks shows increased activity in the hippocampus. The sulci appear larger The gyri appear thicker The lateral ventricles are enlarged Functional imaging shows a decreased metabolic activity in the temporoparietal cortex at resting states indicating defects in episodic memoriesWhich of the following is NOT a symptom commonly shared between Alzheimer’s dementia and Lewy body dementia? a-Hallucination b-Decline in the ability to perform routine tasks c-Loss of language skills d-Gradual memory lossAlzheimer's Disease Alzheimer's disease is a progressive neurodegenerative disorder that affects almost 50 million people worldwide. The cause of Alzheimer's disease is still not well understood. It is thought to be a combination of genetics, lifestyle, and environmental causes. It is also difficult to diagnose Alzheimer's disease during the initial stages of the disease as symptoms can be mistaken for normal ageing. Currently, there is no cure for the disease. Medication can help manage the symptoms but degeneration of brain tissue cannot be stopped or reversed. Currently, the medication that manages the symptoms of Alzheimer's disease is a type of cholinesterase inhibitor. In other words, the medication inhibits the function of cholinesterase and helps in brain functioning and memory. What is the function of cholinesterase in the synapse? How does a cholinesterase inhibitor work in a synapse? Explain how cholinesterase inhibitors are able to increase brain functioning and…
- Which of the following statements best describes the appearance of amyloid plaques and neurofibrillary tangles in Alzheimer's Disease? Amyloid plaques do first appear in neocortical structures spreading to basal ganglia structures, while neurofibrillary tangles are first found in locus coeruleus spreading to the neocortex. Amyloid plaques and neurofibrillary tangles do first appear in basal ganglia structures and then spread progressively to neocortical structures. Amyloid plaques and neurofibrillary tangles are evenly spread throughout basal ganglia, diencephalic and neocortical structures. Amyloid plaques and neurofibrillary tangles do first appear in neocortical structures and then spread progressively to basal ganglia structures.What biological changes take place in older adults brain? What are the biological base of dementia and Alzheimer's?Exactly what does it mean to say that a person is in the "preclinical phase" of Alzheimer's disease? What implications does this have for the progression of the illness?
- Which brain regions show atrophy in Alzheimer’s disease? Select ALL that apply parietal lobe calcarine sulcus prefrontal cortex angular gyrus temporal lobe cingulate gyrusList and describe at least 3 treatments, tests, or other options that would make sense for an Alzheimer's patient's high state of memory loss.If an accurate diagnostic test for Alzheimer’s disease is developed and there is no treatment for the disease, should the test be made available?
- What biological markers have been found that might indicate the presence of Alzheimer's disease in a human being?Alzheimer's disease is a progressive neurological degenerative disorder that affects almost 50 million people worldwide. The cause of Alzheimer's disease is still not well understood. It is thought to be a combination of genetics, lifestyle, and environmental causes. It is also difficult to diagnose Alzheimer's disease during the initial stages of the disease as symptoms can be mistaken for normal aging. Currently, there is no cure for the disease. Medication can help manage the symptoms but degeneration of brain tissue cannot be stopped or reversed. One medication used to manage the symptoms of Alzheimer's disease is a cholinesterase inhibitor. The medication helps to improve brain functioning and memory. What is the function of cholinesterase in the synapse? How does a cholinesterase inhibitor work in a synapse? Explain the function of cholinesterase inhibitor in increasing brain functioning and memorydescribe the stages of Alzheimer's disease