Mutations in Ras are found in a majority of cancers. Which of these mutations will lead to permanent activation of Ras-signaling? Mutations that inhibit Raf-activity Mutations that activate Ras-GAP Mutations that inhibit Ras-GTPase activity Mutations that inhibit Ras-GEF activity O O O O

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter32: The Reception And Transmission Of Extracellular Information
Section: Chapter Questions
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QUESTION 23
Mutations in Ras are found in a majority of cancers. Which of these mutations will lead to permanent activation of Ras-signaling?
Mutations that inhibit Raf-activity
Mutations that activate Ras-GAP
Mutations that inhibit Ras-GTPase activity
Mutations that inhibit Ras-GEF activity
O O 0 O
Transcribed Image Text:QUESTION 23 Mutations in Ras are found in a majority of cancers. Which of these mutations will lead to permanent activation of Ras-signaling? Mutations that inhibit Raf-activity Mutations that activate Ras-GAP Mutations that inhibit Ras-GTPase activity Mutations that inhibit Ras-GEF activity O O 0 O
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