н AICI, one step CI- CI CI sertraline (Zoloft)

Q: One step in the synthesis of the antihistamine fexofenadine (Section 23.5) involves acid-catalyzed…

A: Given Structure: Reaction of A in presence of acid-calatysed hydration of H+ Following products are…

Q: Draw a stepwise mechanism for the following reaction, one step in the synthesis of the…

A: SOLUTION: Step 1: Pitavastatin (Livalo) is a lipid-lowering agent. It is used in the treatment of…

Q: b) Show the major product(s) of the reaction of 4-methylphenylmagnesium bromide (prepared in…

A:

Q: Draw a stepwise mechanism for the following Friedel-Crafts acylation. CH3 AICI, + HCI CH

A: Given reaction,

Q: Sulfur ylides, like the phosphorus ylides of Chapter 21, are useful intermediates in organic…

A: The ion containing -ve charge over C-atom as well as a +ve charge over the heteroatom (S, N and P)…

Q: Explain why protonating aniline has a dramatic effect on the compound’s UV spectrum, whereas…

A: Protonation is the addition of a proton molecule to make a conjugate acid. Each and every structure…

Q: Draw a stepwise mechanism for the following reaction, a key step in the synthesis of the…

A: Proton abstraction from the acid HCl. Nucleophilic attack on to the carbonyl carbon by the lone…

Q: Acid-catalyzed dehydration of B-hydroxy carbonyl compounds occurs by the mechanism discussed in…

A: The mechanism for the given reaction is given below

Q: Draw a stepwise mechanism for the sulfonation of an alkyl benzene such as A to form a substituted…

A:

Q: The ionones are fragrant substances present in the scent of iris and are used in perfume. A mixture…

A: Ionones are a group of compounds that are cyclic in nature and they have a specific aroma in their…

Q: Draw a stepwise mechanism for the attached reaction, which involves two Friedel–Crafts reactions. B…

A: Various types of mechanisms are studied in organic chemistry. One of them is electrophilic…

Q: Diphenhydramine, the antihistamine in Benadryl, can be prepared by thefollowing two-step sequence.…

A: The structure of diphenhydramine has to be given.

Q: (b) Answer the following questions based on the compounds below. Jawab soalan berikut berdasarkan…

A: Given :  1. Which compound has the higher boiling point ?  2. Draw SN2 mechanism for the reaction of…

Q: One step in the synthesis of the antihistamine fexofenadine involves acid-catalyzed hydration of the…

A: Acid catalyzed hydration of alkynes- Acid catalyzed hydration of alkynes produce ketone.…

Q: Draw a stepwise mechanism for the following reaction that forms ether D. D can be converted to the…

A: A stepwise mechanism for the following reaction that forms ether D has to be drawn.

Q: Decytospolides A and Bare fungal natural products that are toxic to some cancer cells, In a…

A: Concept : 1) NaH is used as base for deprotonation.  2) Grignard reagent is used as nucleophile here…

Q: Identify products A and B from the given 1H NMR data. Treatment of CH2=CHCOCH3 with one equivalent…

A: Addition of a molecule over a double bond is called addition reaction. After addition of HCl, three…

Q: Draw a stepwise mechanism for the following Robinson annulation. This reaction was a key step in a…

A:

Q: One synthesis of the cholesterol-lowering drug atorvastatin involves the construction of the pyrrole…

A: The organic conversions take place in more than one step with the help of various reagents.

Q: Slow addition of organolithium reagent A to B afforded C, an intermediate in the synthesis of the…

A: Stepwise mechanism for this process can be drawn as

Q: Draw a stepwise mechanism for the sulfonation of an alkyl benzene such as A to form a substituted…

A: This reaction is the electrophilic substitution reaction followed by basic medium

Q: Treatment of ketone A with LDA followed by CH3CH2I did not form the desired alkylation product B.…

A: The product formed in the reaction is shown below.

Q: Draw a stepwise mechanism for the intramolecular Friedel–Crafts acylation of compound A to form B. B…

A: Concept introduction: The Friedel-Craft acylation is a type of electrophilic substitution reaction.…

Q: Which compound is the most reactive toward electrophilic aromatic substitution? BO O D с

A: In an electrophilic substitution reaction, an electrophile substitutes a hydrogen atom and attaches…

Q: 1. Draw and name all the products (A- F) from the reactions of compound X with several reagents. B+C…

A: We have to draw and name all the product for the following given reactions as follows in step 2:

Q: Draw a stepwise mechanism for the sulfonation of an alkyl benzene such as A to form a substituted…

A: Stepwise mechanism for the sulfonation of alkyl benzene to form a substituted benzene sulfonic acid…

Q: Identify the reagents X in the following scheme ОН NaBH4 with H30+ KMN04 with H30+ O All are correct…

A:

Q: Draw a stepwise mechanism for the conversion of lactone A to ester B using HCl in ethanol. B is…

A: In the first step of the mechanism the carbonyl group undergoes protonation followed by attack of…

Q: Draw a stepwise mechanism for the following intramolecular reaction, which is used in the synthesis…

A: The given compound is the female sex hormone Estrone.

Q: (R)-Carvone, the major component of the oil of spearmint, undergoes acid-catalyzed isomerization to…

A: Acid-catalyzed isomerization of R carvone leads to the product carvacrol which is more stable than…

Q: What is the major product generated when p-t-butyl aniline undergoes Friedel-Crafts alkylation…

A:

Q: CI I II IV

A: The correct answer is given below

Q: Devise a stepwise mechanism for the following reaction, a key step in the synthesis of the…

A: Given:

Q: What steps are needed to convert benzene into p-isobutylacetophenone, a synthetic intermediate used…

A: First we need to react the benzene with the below mentioned compound in presence of AlCl3  Than the…

Q: Draw a stepwise mechanism for the following reaction that forms ether D. D can be converted to the…

A: Since KOC(CH3)3 is a strong base. Hence it will take proton from the OH group and convert it into O-…

Q: An allylic alcohol contains an OH group on a carbon atom adjacent to a C—C double bond. Treatment of…

A: The given reaction occurs via the formation of carbonation and this carbonation undergoes…

Q: Draw a stepwise mechanism for the following reaction that forms ether D. D can be converted to the…

A:

Q: Draw a stepwise mechanism for the following intramolecular reaction, which is used in the synthesis…

A: The mechanism for the following reaction is as follows:

Q: Draw the major organic product of the reaction of aniline with excess methyl iodide. Include Draw…

A: Given reaction,

Q: Draw a stepwise mechanism for the conversion of lactone A to ester Busing HCl in ethanol. B is…

A:

Q: 4-Methylpyridine reacts with benzaldehyde (C6H5CHO) in the presence of base to form A. (a) Draw a…

A:

Q: Draw a stepwise mechanism for the following reaction, a key step in the synthesis of the…

A: Step in the synthesis of the anti-inflammatory drug  Celebrex is shown below,

Q: Devise a synthesis of each compound from aniline (C6H5NH2) as startingmaterial.

A:

Q: Draw a stepwise mechanism for the formation of A from an alcohol and acid chloride. A was converted…

A: A species with a larger size can easily accommodate negative charge. In other words, in a large size…

Q: Draw a stepwise mechanism for the following reaction. The four-membered ring in the starting…

A: The four membraned ring in the starting material and product is called as beta-lactum ring. DBN is a…

Q: Draw a stepwise mechanism for the following reaction, a key step in thesynthesis of the…

A:

Q: (R)-Carvone, the major component of the oil of spearmint, undergoes acid-catalyzed isomerization to…

A: The protonation of (R)- carvone is show below.

Q: Draw a stepwise mechanism for the intramolecular Friedel–Crafts acylation of compound A to form B. B…

A: Friedel-Crafts Alkylation is used to alkylate aromatic compounds like benzene. This reactions makes…

Q: Draw a stepwise mechanism for the following reaction, a key step in the synthesis of ticlopidine, a…

A: This reaction mechanism contains two parts. First the dissociation of acetal into ethane-1,2-diol…

Organomagnesium compounds

The interaction of alkyl halide with Mg metal in a suitable ether solvent is the common method for the synthesis of the Grignard reagent.

Hydrolysis Grignard Reactions and Reduction

Organomagnesium halides are Grignard reagents. Francois Auguste Victor Grignard, a French chemist who received the Nobel Prize in Chemistry in 1912, created these highly useful reagents.