НА HO HO R isomer inactive enantiomer S isomer active enantiomer

Q: Propose structural formulas for compounds A and B.

A: Various mechanisms are used in organic chemistry. The mechanism tells which bonds are formed and…

Q: It is well reported that the antiallergic activity of Claritin (loratadine) is not only the result…

A: Descarboethoxyloratadine is the active metabolite of Loratadine. It is formed by CYP mediated…

Q: The reaction of thioacetamide (CH3CSNH2) with Cu2+ forms a _________.   A. Sulfide   B. Sulfite…

A: The reaction will be:   Cu (OH)2 (aq) + CH3CSNH2 (aq)   --------- >  CuS(s) + CH3CONH2 (aq) +…

Q: (2R, 3S) -3-phenylbutan-2-ol tosylate undergoes E2 removal when treated with sodium ethoxide. Draw…

A: Note : In E2 elimination OTs, H and ethoxide ion in one plane (anti periplanar transition state)…

Q: An acid-base reaction of (R)-sec-butylamine with a racemic mixture of 2-phenylpropanoic acid forms…

A: The reaction involved betweem (R)-sec-butylamine and racemic mixture of 2-phenylpropanoic acid is as…

Q: II. Draw the structures of the ff: A. N-ethyl-N-phenylpropanamide B. 3-hydoxy-N-methyhexanamide C.…

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Q: 1.2 The following is a drug used to treat multi-drug resistant strains of Falciparum malaria CH3 H3C…

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Q: An acid-base reaction of (R)-sec-butylamine with a racemic mixture of 2- phenylpropanoic acid forms…

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Q: 3. Draw the structure of cyclopentylisopropylamine. Classify it as 1º, 2° or 3°.

A: The structure of cyclopentylisopropylamine is as follows,

Q: Draw the structure of sodium tetradecyl sulfate and ciprofloxacin and state how the activity of the…

A: The key components associated with a molecule that is responsible for providing the characteristic…

Q: Is the acid-catalyzed hydrolysis of acetamide a reversible or an irreversible reaction? Explain.

A: The acid-catalyzed hydrolysis of acetamide is an irreversible reaction. This is because the last…

Q: Quinapril (trade name Accupril) is used to treat high blood pressure and congestive heart failure.…

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Q: Ammonia and amines react with epoxides with the same stereospecificity as anionic nucleophiles. Draw…

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Q: When 2-heptine was treated with aqueous sulfuric acid containing mercury(II) sulfate, two products…

A: When 2-heptyne was treated with aq. H2SO4 containing mercury (II) sulphate  There are two products…

Q: An acid–base reaction of (R)-sec-butylamine with a racemic mixture of 2-phenylpropanoic acid forms…

A: The reaction between racemic mixture of 2 -phenylpropanoic acid with (R) -sec-butylamine is an acid…

Q: A commonly formed side product during the Hoffman rearrangement is a urea. When butanamide is…

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Q: t)which B the fallowing Statements is true regardirg N- phenylocetamide ? 5aka a cetanilide Lamide…

A: This question is related to general organic chemistry. N-phenyl acetamide has an amide functional…

Q: Give specific examples for the synthesis of the compounds bearing the following functional groups.…

A: Since you have asked multiple questions, we will solve the first 3 part for you. If you want any…

Q: The product formed by the reaction of CH3CO,H with HN-CH3 H2C -CH3 is properly named a.…

A: The reactants given are CH3COOH and .

Q: Direct alkylation of D by treatment with one equivalent of LDA and CH3I does not form ibuprofen.…

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Q: Explain how (NH2CH2CH2NH2)2C03* catalyses the hydrolysis of compound I. H,N

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Q: Explain the observation that attempted Fischer esterification of 2.4,6-trimethylbenzoic acid with…

A: The solution is given below -

Q: Which one of the following statements best describes the chemistry of ring A? D E он OH A Oleandrin…

A: This question is related to description of sugar for a particular ring. Follow the detailed…

Q: 11. Compound A, C9H17N, is an optically inactive alkaloid, containing a tertiary amine that is not…

A: TERTIARY AMINE: It is also known as 3∘ amine. An amine chemical functional group in which nitrogen…

Q: Bicyclic ketone A rapidly equilibrates with a stereoisomer upon treatment with strong base, but…

A: The given ketones are represented as follows:

Q: Moxisylyte, an a-adrenergic blocker, is used as a peripheral vasodilator. Propose a syn- thesis for…

A: m- Cresol reacts with propene in the presence of phosphoric acid gives thymol, thymol undergoes…

Q: There are a number of pharmacokinetic strategies available to change the absorption of a lead…

A: Polarity of a molecule can be decreased either by polar groups or introducing non-polar groups

Q: Rank the following compounds in order of increasing basicity: I. p-nitroaniline II.…

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Q: Complete the following multistep synthesis, depicting the possible stereochemical control in the…

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Q: Molecules of 6,6'-dinitrobiphenyl-2,2'-dicarboxylic acid have no tetrahedral chiral center, and yet…

A: Chirality is defined as carbon atom bonded to four different groups, which are optically active.…

Q: The following structure possesses a carbonyl (C-O) functional group with prochiral 'faces', and a…

A: Structure is viewed from that side from where, Hydrogen in above side.  Above group means the group…

Q: Which of the following substituent is a meta-directing deactivator?   a amino group   b…

A: ->Substituents which are electron donating group that are activating group and increases the…

Q: What are the R/S configurations of the sterogenic centers in this molecule?

A: In any molecule, a stereogenic center is a point of location at which interchange of any two groups…

Q: Draw the structure of the product obtained when this amine is treated with excess iodomethane and…

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Q: Treatment of pentanedioic (glutaric) anhydride with ammonia at elevated temperature leads to a…

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Q: yニ,ニ N P 'CI HO, Q んこんこんn S R to `Br

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Q: Which of the following substituent is an ortho/para-directing activator and an ortho/para-directing…

A: Ortho/para and meta directing groups on benzene are depends upon the nature of the groups. If the…

Q: 10.₁ amide? A. one equivalent B. two equivalents C. this conversion is not possible D. one…

A: Following questions are belongs to the reaction mechanism.

Q: Draw the structure of the product obtained when this amine is treated with excess iodomethane and…

A: This this Hoffman exhaustive methylation reaction. Step 1- Quartanry Amonoum salt formed by reaction…

Q: What reagents are needed to convert phenylacetonitrile (C6H5CH2CN) to each compound: (a)…

A: a.

Q: A chemist synthesized compound X as a racemic mixture. When the ketone group in X was enzymatically…

A: Given: A reaction takes place in which a racemic mixture gives a single product with 100% yield. To…

Q: General Structure-Function Association for Different Benzodiazepine Modifications. e.g. CH, Methyl…

A: Due to technical error ,unable to provide you the solution. Please resubmit the question once again

Q: Although ibuprofen is sold as a racemic mixture, only the S enantiomer acts as an analgesic. In the…

A: Given:

Q: What product is obtained from the reaction of N,N-dimethylaniline with nitrous acid? A.…

A: The product obtained from the reaction of N,N-dimethylaniline with nitrous acid is given below.

Q: An acid–base reaction of (R)-sec-butylamine with a racemic mixture of 2phenylpropanoic acid forms…

A: Racemic mixture of 2-phenylpropanoic acid consists of R and S forms (enantiomers). Both these forms…

Q: 5. The enantiomers of 1-amino-2-propanol were separated and recovered as their hydrochloride salts:…

A: a. Streochemical formula for the both isomers are shown as below: b.The enantiomers can rotate the…

Q: Threonine is a naturally occurring amino acid that has two stereogenic centers. a. Draw the four…

A: a) The four stereoisomers of threonine are -

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.