Product Rule Given the following traits that the parents have, assign the letters H for hair type. E for eyelids, and L for lip color. Parent 1: Homozygous curly hair Homozygous short eyelids Homozygous pale lips (dominant) Genotypes Probability (fraction) (Parent 1) Parent 2: Heterozygous straight hair Heterozygous long eyelids Homozygous red lips (recessive) Probability (fraction) (Parent 2) Probability (fraction) 3. What is the probability (in percentage) that their child will inherit the following genotypes? Homozygous curly hair, Homozygous short eyelids, Heterozygous pale lips Probability=%
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- FAlpQLSfiOhfAvlhxzCSiUll_6rt-nU5b0WI73UmWOxkOw8OCwk01ng/formResponse B 1 2 Bb x Bb b 4 The fur in both parents in this cross is * 1 B B Bb x Bb b 3 4 brown black O homozygous dominant homozygous recessive 3. 近Colored beans to represent the gene for a certain trait of garden pea. (60 pieces of the same size and shape; 30 pieces of which are of different colors from rest) Procedures: 1. Place the 30 pieces beans (one color) to one container and the other 30 pieces to the other container. Assign which color of beans will represent dominant and recessive genes of a specific trait of garden pea 2. Label the paper container as First Parent P1, male and other P1 female 3. At random, segregate the beans on the Lab table. Assume fertilization occurs and First filial generations (F1) are formed 4. Categorize the formed First filial generations 5. Put all the beans in one container. Assume that all the first filial generations undergo self-fertilization 6. Pick up the beans by two from the container without looking at it and collect the second Filial generation (F2) 7. Categorize the formed Second filial generations into two (2) phenotype, and three (3) genotype classes 8. Fill up Table 15.1 for the…5 & :56M ******* 24 DIHYBRID CROSSES DRV 0 Stv T alı A @ zladenA 9160p2-id2 bns obidalbaneoviene da II\ MOD YR 21 $59A ... Create a dihybrid cross and determine the expected phenotypic percentages of the offspring of two corn plants both of which are heterozygous for colour and texture (RrTt X RrTt). Don't forget to include clear let statements, and follow the all six steps taught on solving genetics problems. insig moni nellog: bna. zoom
- PEDIGREES: Problem (continued) This pedigree shows the inheritance of cystic fibrosis in this family. I • QUESTIONS ••. 5. What is the genotype of individual II-3? Use the letter "f" to 1 2 represent the disease allele. II 1 2 3 6. Individuals II-I and II-2 are sisters. Explain how it is possible for one sister to have cystic fibrosis but NOT the other. III 1 2 3SUBJECT: GENETICS Topic: Probability 1. Consider albinism a trait to occur in a human family. If two parents areheterozygous for such trait, the probability of having a normally pigmented child is 3//4 and having an albino child is ¼. What is the probability that 2 will be normal and 1 will be albino?A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. What if the couple wanted prenatal testing so that a normal fetus could be aborted?
- A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. What is the chance that this couple will have a child with two copies of the dominant mutant gene? What is the chance that the child will have normal height?A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. Should the parents be concerned about the heterozygous condition as well as the homozygous mutant condition?dd-ons Help в I U A Calibri 12 三 三1 |:三 6. Consider a guinea pig with a homozygous genotype and a white fur color phenotype. a. What is the probability this parent will produce a gamete with the dominant allele? b. What is the probability this parent will produce a gamete with the recessive allele? C. If 31 sperm cells are collected from this guinea pig, how many would you expect to have the recessive allele (as determined by sequencing the gene)? !!!
- Purple flowers are dominant to white flowers. Identify the phenotypefor the following genotype Ff, FF, ff and determine if the genotype is heterozygous or homozygous. * For each row, you should select two columns. Purple flowers White flowers Heterozygous Homozygous Ff FF ff Brown eyes are dominant to blue eyes. Identify the phenotype for the following genotype BB, Bb, bb and determine if the genotype is heterozygous or homozygous. * 口 ロ口NAME: Patterns of Inheritance Worksheet 1. True Breeding Parental Cross A homozygous dominant purple flowered plant is crossed with a homozygous recessive white flowered plant. a. What are the genotypes of the parent plants? (Use the Punnett square to determine the outcomes of this cross. Remember to place the gametes along the left side and top of the square. (P=Purple, p=white) b. What is the genotype of all F₁ plants? 1 b. c. What is the phenotype of all F₁ plants? C. d. How many plants out of 4 will produce white flowers? d. a. 2. Monohybrid Cross: The F₁ offspring from the above problem are allowed to self fertilize. a. What are the genotypes of the F₁ parents? a. (Use the Punnett square to determine the outcomes of this cross. Remember to place the gametes along the left side and top of the square.) b. What is the genotype ratio for this cross? c. What is the phenotype ratio for this cross? d. How many plants out of 4 will produces white flowers? d. b. C.PATERNITY TESTING Family Inheritance of STR AIleles (D13S317) 110 11 14 Father 12 14 Child al 14 Child a2 11 12 Child a3 12 Mocher A). What is the meaning of the numbers above the peaks for the father? B). How many Child/children belong to both parents? C). Define STR D). Define D13S317