Answered: Question: A woman with normal teeth had…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Faulty Tooth Enamel Formation
Amelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an autosomal dominant and X-linked dominant pattern.

The expression of AI disorder is determined by mutations in the autosomal alleles. One copy of the mutated allele (A) will cause the disorder. The severity of the disorder is determined by mutations in a gene carried on the X chromosome. Normal (or non-severe) abnormality (X^N) is dominant over the abnormality (or severe) (Xⁿ) allele. In the absence of the autosomal dominant allele, the abnormality gene on the X chromosome is notexpressed.

Question:
A woman with normal teeth had four children with a man with non-severe form of AI:

A boy was born without amelogenesis imperfecta
A girl was born without amelogenesis imperfecta
A boy was born with severe amelogenesis imperfecta
A boy was born with non severe amelogenesis imperfecta

Identify the parental genotypes.
Complete the Punnett square for the parental cross, and identify the possible phenotypic ratios of the children.

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