Ras is a proto-oncogene that is within the EGF pathway. The EGF receptor can activate the cell division pathway only when the EGF ligand binds to the receptor. A gain of function mutation occurs in only one copy of the Ras gene. What are all the possible consequences of this? Select all that apply. Group of answer choices The cell will undergo constant cell division The cell will still be normal as only one copy of Ras is mutated. Both copies must be mutated for the cell to undergo constant cell division There will be an increase of EGF ligands present in the cell The EGF receptor will always be active even with no EGF ligands bound and activate the pathway Ras will always be active and activate the proteins downstream that will turn on cell division Ras will be under the influence of the EGF receptor and will only activate if the EGF ligand is bound to the receptor
Ras is a proto-oncogene that is within the EGF pathway. The EGF receptor can activate the cell division pathway only when the EGF ligand binds to the receptor. A gain of function mutation occurs in only one copy of the Ras gene. What are all the possible consequences of this? Select all that apply. Group of answer choices The cell will undergo constant cell division The cell will still be normal as only one copy of Ras is mutated. Both copies must be mutated for the cell to undergo constant cell division There will be an increase of EGF ligands present in the cell The EGF receptor will always be active even with no EGF ligands bound and activate the pathway Ras will always be active and activate the proteins downstream that will turn on cell division Ras will be under the influence of the EGF receptor and will only activate if the EGF ligand is bound to the receptor
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Ras is a proto-oncogene that is within the EGF pathway. The EGF receptor can activate the cell division pathway only when the EGF ligand binds to the receptor. A gain of function mutation occurs in only one copy of the Ras gene. What are all the possible consequences of this? Select all that apply.
Group of answer choices
The cell will undergo constant cell division
The cell will still be normal as only one copy of Ras is mutated. Both copies must be mutated for the cell to undergo constant cell division
There will be an increase of EGF ligands present in the cell
The EGF receptor will always be active even with no EGF ligands bound and activate the pathway
Ras will always be active and activate the proteins downstream that will turn on cell division
Ras will be under the influence of the EGF receptor and will only activate if the EGF ligand is bound to the receptor
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